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Effect of platelet-rich plasma and knee mobilization techniques and dry needling in knee osteoarthritis patients

Comparison of the effect of platelet-rich plasma and knee mobilization techniques and dry needling in knee osteoarthritis patients

Status
Recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20240211060958N1
Enrollment
76
Registered
2024-05-15
Start date
2024-06-21
Completion date
Unknown
Last updated
2024-08-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

knee osteoarthritis. Bilateral primary osteoarthritis of knee

Interventions

Intervention 1: Intervention group: dry needling and knee mobilization. Intervention 2: Intervention group: platelet-rich plasma. Intervention 3: Control group: placebo.

Sponsors

Kerman University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
45 Years to 70 Years

Inclusion criteria

Inclusion criteria: The patients were between the ages of 45 and 70 years old The presence of moderate osteoarthritis symptoms (grade 2-3 of the Kellgren-Lawrence classification system) The presence of trigger point (latent or active) in the muscles around the hip and knee joints.

Exclusion criteria

Exclusion criteria: Patients with severe inflammation/swelling of the knee Any history of injection/aspiration of the knee joint during the last year Any previous fracture of the spine or lower limbs Associated neurological pathology Vestibular disorders Systemic disease (rheumatoid arthritis or diabetes) Patients with blood disorders (such as hemophilia or thalassemia), cancer, or if they are taking taking anticoagulants drugs

Design outcomes

Primary

MeasureTime frame
1.Pain intensity. Timepoint: Before, After and 2month follow up. Method of measurement: Visual analog scale.

Secondary

MeasureTime frame
Knee disability index. Timepoint: Before, After and 2month follow up. Method of measurement: WOMAC questionnaire and KOOS questionnaire.;Knee range of motion. Timepoint: Before, After and 2month follow up. Method of measurement: Goniometer.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactTahereh Rezaeian

Kerman University of Medical Sciences

tahere.rezaiyan@gmail.com+98 34 3132 5700

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026