Obesity and weight gain. Overweight and obesity
Conditions
Interventions
Intervention 1: Control group: placebo containing 500 mg starch which will consume two-times per day with lunch and dinner meals for 8 weeks. Placebo with the same color, smell and size with the drug
Sponsors
Islamic Azad University
Eligibility
Sex/Gender
All
Age
18 Years to 50 Years
Inclusion criteria
Inclusion criteria: male and female between 18-50 yr old body mass index equal-higher than 27.5
Exclusion criteria
Exclusion criteria: pregnancy and lactation in females any type of diagnosed disease including neoplasm, kidney and liver diseases thyroid disorders metabolic disorders intake of pro-kinetics and antacid drugs mental disorders and depression antibiotic intake probiotic, prebiotic and synbiotic intake intake of foods containing probiotic people under a certain diet gastrointestinal disorders including malabsorptive diseases, constipation and diarrhea
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Weight loss. Timepoint: at the baseline and after two month of intervnetion. Method of measurement: calibrated scale.;Population of Firmicutes phyla. Timepoint: at the baseline and after two month of intervnetion. Method of measurement: realtime polymerase chain reaction.;Population of Bacteroidetes phyla. Timepoint: at the baseline and after two month of intervnetion. Method of measurement: realtime polymerase chain reaction.;Population of Actinobacteria phyla. Timepoint: at the baseline and after two month of intervnetion. Method of measurement: realtime polymerase chain reaction.;Population of proteobacteria phyla. Timepoint: at the baseline and after two month of intervnetion. Method of measurement: realtime polymerase chain reaction.;Population of butyrogenic bacteria including butyrovibrio, facali prausnitzi, clostridium and roseburia. Timepoint: at the baseline and after two month of intervnetion. Method of measurement: realtime polymerase chain reaction. | — |
Secondary
| Measure | Time frame |
|---|---|
| Short chain fatty acids including acetate, propionate, butyrate and valerate. Timepoint: at the baseline and end of study. Method of measurement: Gas chromatography-Mass spectrometery. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactSeyedeh Neda Mousavi
Zanjan University of Medical Sciences
Outcome results
None listed