Eltrombopag and Platelet Recovery in Patients with Dengue Fever

Effect of Eltrombopag Olamine on Platelet Recovery and Bleeding Complications Among Dengue Patients with Severe Thrombocytopenia_ A Randomized Controlled Trial

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20240208060941N3

Enrollment

Registered

2025-03-26

Start date

2024-10-21

Completion date

Unknown

Last updated

2025-07-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Dengue Fever. Dengue fever [classical dengue]

Interventions

Intervention 1: Intervention group: Tab Eltrombopag Olamine 25 mg will be given orally for 3 days once a day alongwith routine medical care. Intervention 2: Control group: Oral Glucose tablets will be

Eligibility

Sex/Gender

All

Age

14 Years to 75 Years

Inclusion criteria

Inclusion criteria: Adult patients Dengue NS1 Positive Platelet count less than 100

Exclusion criteria

Exclusion criteria: MP slide positive Presence of any other warning signs

Design outcomes

Primary

Measure	Time frame
Change in platelet counts. Timepoint: 7 Days after intervention. Method of measurement: Daily complete blood picture with manual platelet counts.;Incidence of bleeding complications. Timepoint: Before intervention and daily for 7 days after invention. Method of measurement: Clinical monitoring.	—

Secondary

Measure	Time frame
Inflammatory markers. Timepoint: Day 7 of enrollment. Method of measurement: Serum Ferritin, Serum Albumin and Lipid profile will be monitored.	—

Countries

Pakistan

Contacts

Public ContactFatima Masud

Pak-Emirates Military Hospital, Rawalpindi

fatimamasud454@gmail.com+92 335 2799000

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026