end stage renal disease. End stage renal disease
Conditions
Interventions
Intervention 1: Intervention group 1: Pregabalin group. Intervention 2: Intervention group 2: Sertraline group.
Sponsors
Pak Emirates Military Hospital
Eligibility
Sex/Gender
All
Age
19 Years to No maximum
Inclusion criteria
Inclusion criteria: Patients from both genders greater than 18 years of age Patients on twice weekly hemodialysis for at least 6 months Patients having uremic pruritus for more than 6 weeks
Exclusion criteria
Exclusion criteria: Patients with dermatological or systemic diseases associated with pruritis (such as acute hepatitis, chronic liver disease, pregnancy, and hypothyroidism) Patients with mental health issues affecting their ability to respond to the 5-D Itch Scale (such as psychosis, obsessive-compulsive disorder, or substance abuse) Patients on thrice-a-week haemodialysis schedule Not consenting to participate
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Change in severity of pruritis. Timepoint: 6 weeks post initiation of treatment. Method of measurement: The 5-D Itch Scale (Urdu version). | — |
Countries
Pakistan
Contacts
Public ContactMuhammad Iqbal
Pak Emirates Military Hospital
Outcome results
None listed