The effect of Nik Ara Company's cleanser in the improvement of patients with acne vulgaris

Investigating the anti-acne effect of a cleanser containing myrtle essential oil entrapped in chitosan bead from Nik Ara Company on reducing acne, levels of moisture, pH, fat, elasticity, and skin melanin in patients with acne vulgaris

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20240207060931N1

Enrollment

Registered

2024-02-25

Start date

2024-04-03

Completion date

Unknown

Last updated

2024-03-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Acne vulgaris. Acne vulgaris

Interventions

Intervention 1: Intervention group: Patients undergo clinical studies before starting the treatment, and the condition of their skin lesions is recorded using a high-contrast digital camera to accurat

Eligibility

Sex/Gender

All

Age

10 Years to No maximum

Inclusion criteria

Inclusion criteria: Patients with mild to moderate acne vulgaris (based on the definition of comedone, papule, and pustule lesions). Minimum age of 12 people Willing to participate in the study and complete the consent form.

Exclusion criteria

Exclusion criteria: People with congenital or acquired immune deficiency People with atopy and eczema and chronic skin diseases People with severe acne that is accompanied by nodules and cysts that require systemic treatments Taking anti-acne treatments in the last 4 weeks such as peeling, laser, and antibiotic drugs Pregnant women, lactating women and polycystic ovary syndrome patients People using drugs that cause acne, such as oral and topical steroids and anticonvulsants

Design outcomes

Primary

Measure	Time frame
Changes in acne grade. Timepoint: Before the intervention and 56 days after the intervention. Method of measurement: Acne grade will be calculated based on the GAGS system (Global Acne Grading System) on days 0 and 8 weeks after using the drug and placebo.;Changes in skin pH. Timepoint: Before the intervention and 56 days after the intervention. Method of measurement: Skin pH values will be measured by the MST1000 device.;Changes in skin moisture. Timepoint: Before the intervention and 56 days after the intervention. Method of measurement: Skin moisture levels will be measured by the MST1000 device.;Changes in skin fat level. Timepoint: Before the intervention and 56 days after the intervention. Method of measurement: Skin fat level values will be measured by the MST1000 device.;Changes in skin elasticity. Timepoint: Before the intervention and 56 days after the intervention. Method of measurement: Skin elasticity values will be measured by the MST1000 device.	—

Measure

Time frame

Changes in acne grade. Timepoint: Before the intervention and 56 days after the intervention. Method of measurement: Acne grade will be calculated based on the GAGS system (Global Acne Grading System) on days 0 and 8 weeks after using the drug and placebo.;Changes in skin pH. Timepoint: Before the intervention and 56 days after the intervention. Method of measurement: Skin pH values will be measured by the MST1000 device.;Changes in skin moisture. Timepoint: Before the intervention and 56 days after the intervention. Method of measurement: Skin moisture levels will be measured by the MST1000 device.;Changes in skin fat level. Timepoint: Before the intervention and 56 days after the intervention. Method of measurement: Skin fat level values will be measured by the MST1000 device.;Changes in skin elasticity. Timepoint: Before the intervention and 56 days after the intervention. Method of measurement: Skin elasticity values will be measured by the MST1000 device.

—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactMohammad Hadi Nematollahi

Kerman University of Medical Sciences

mh.nematollahi@yahoo.com+98 34 3325 7448

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026