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Effect of Propofol in coronary bypass surgery

Comparison of outcomes between Propofol and Dexmedetomidine on extubation time and vital signs in patients with post- coronary artery bypass grafting in Open heart Intensive Care Unit

Status
Recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20240207060924N1
Enrollment
92
Registered
2024-02-17
Start date
2024-02-20
Completion date
Unknown
Last updated
2024-03-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Comparison of Outcomes Between Propofol and Dexmedetomidine in Post-Coronary Artery Bypass Graft Patients.

Interventions

Intervention 1: First intervention group: (P) that we infuse 10 cc per hour (10 cc/hr) for 4 to 6 hours from a vial of propofol 10% (manufactured by B. Braun, Germany). Intervention 2: Second interven

Sponsors

Arak University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
35 Years to 80 Years

Inclusion criteria

Inclusion criteria: Having informed consent Patients must meet inclusion criteria, i.e. be elective and referred for open heart surgery only Age should be between 35 and 80 years old Performed by the same surgeon The maximum duration of the surgery must be 6 hours All were operated with a cardiopulmonary pump Valve surgery should not be performed at the same time as CABG

Exclusion criteria

Exclusion criteria: Patient is not a candidate for elective CABG surgery Duration of surgery is more than 6 hours Patients have not had surgery outside of the cardiopulmonary pump Patients outside the 35-80 age range The patient has the right to withdraw at any stage of the research

Design outcomes

Primary

MeasureTime frame
Mean arterial blood pressure. Timepoint: Measurement of mean arterial blood pressure at 5, 15, 30, 45, 60, 90, 120, 150 minutes after entering the ward. Method of measurement: Pulse Oximeter.;Pulse rate. Timepoint: Measurement of pulse rate at 5, 15, 30, 45, 60, 90, 120, 150 minutes after entering the ward. Method of measurement: Pulse Oximeter.;Oxygen saturation. Timepoint: Measurement of Oxygen saturation at 5, 15, 30, 45, 60, 90, 120, 150 minutes after entering the ward. Method of measurement: Pulse Oximeter.;Extubation time. Timepoint: The duration of extubation from the time of admission to the Open Heart Intensive Care Unit. Method of measurement: Questionnaire.;Length of stay in the Unit. Timepoint: The duration of the stay in the Intensive Care Unit of the Open Heart surgery after the operation. Method of measurement: Questionnaire.;Length of hospitalization. Timepoint: The duration of the stay in the hospital. Method of measurement: Questionnaire.;Ramsay Score. Timepoint: Measurement of Ramsay score at 5, 15, 30, 45, 60, 90, 120, 150 minutes after admission to the unit. Method of measurement: Questionnaire.;Mortality. Timepoint: Measurement of the number of mortality events in the study population. Method of measurement: Questionnaire.;Age. Timepoint: Registration of patient age. Method of measurement: Questionnaire.;Sex. Timepoint: Registration of patient sex. Method of measurement: Questionnaire.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactTaha Rafiei

Arak University of Medical Sciences

taharafiei@yahoo.com+98 86 3313 3147

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026