Skip to content

Investigating the therapeutic effects of microneedling, TCA 50% and the combination of both in limb vitiligo

Comparison of therapeutic effects of 3 methods of microneedling with TCA 50%, microneedling and peeling TCA 50% each alone in acral vitiligo

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20240204060900N1
Enrollment
21
Registered
2024-02-07
Start date
2023-07-23
Completion date
Unknown
Last updated
2024-03-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

acral vitiligo. Vitiligo

Interventions

Intervention 1: Microneedling with Dr. Pen brand microneedling with a length of 1.5 mm every three weeks in one area, 4 steps. Intervention 2: Intervention group: TCA (Trichloroacetic acid) peeling 50

Sponsors

Esfahan University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
11 Years to 60 Years

Inclusion criteria

Inclusion criteria: Absence of active vitiligo for 2 years Not receiving treatment in the last 3 months Lack of sensitivity to the studied drugs Having at least three depigmented patches at the end of the limb

Exclusion criteria

Exclusion criteria: Pregnancy and breastfeeding A history of scar and keloid formation in the body Received treatment in the last three months Presence of active vitiligo in the last 2 years

Design outcomes

Primary

MeasureTime frame
Lesion recovery score based on size. Timepoint: The recovery rate of the lesions after the end of the treatment and three months after the end of the treatment. Method of measurement: Observation of photos before and after treatment by 2 dermatologists and grading based on the degree of recovery.

Secondary

MeasureTime frame
Patient satisfaction score. Timepoint: Patient satisfaction score after treatment and 3 months after completion of treatment. Method of measurement: Visual Analog Scale Questionnaire.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactAli Ghadirian

Esfahan University of Medical Sciences

alighadirian@yahoo.com+98 31 3822 0000

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026