Breast cancer. Malignant neoplasm of nipple and areola, unspecified female breast
Conditions
Interventions
Intervention 1: Intervention group: Intervention group: first intervention group: invasive ductal carcinoma, second intervention group: fibroadenoma, third intervention group: fibrocystic. After mammo
Sponsors
Esfahan University of Medical Sciences
Eligibility
Sex/Gender
Female
Inclusion criteria
Inclusion criteria: The study population includes women who will refer to the surgery department of Anahid Clinic for breast tissue tumor surgery.
Exclusion criteria
Exclusion criteria: Noisy images with artifacts that have no diagnostic value or lead to incorrect diagnosis. Women with a history of heart surgery. Suspicious findings can only be seen in ultrasound images, while no evidence of the existence of a tumor can be seen in mammography images. Mammography and ultrasound images of BI-RADS groups 1,2, and 3 with insufficient follow-up period. Pregnant or lactating women.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Invasive breast cancer positivity for Estrogen receptors. Timepoint: Estrogen receptor testing is performed when the cancer has recurred or metastasized. Method of measurement: Container/tube: container containing 10% formalin, sample type: tissue in 10% formalin or tissue block, sample volume: one paraffin block or seven slides of colorless and positively charged tissue cut in dimensions of 4 to 5 microns and kept for one Dry at 60°C for an hour. Estrogen receptor detection in paraffin-fixed tissue sections is performed using a specific kit detection system.;Invasive breast cancer positivity for Progesterone receptors. Timepoint: Progesterone receptor testing is performed when the cancer has recurred or metastasized. Method of measurement: Container/tube: container containing 10% formalin, sample type: tissue in 10% formalin or tissue block, sample volume: one paraffin block or seven slides of colorless and positively charged tissue cut in dimensions of 4 to 5 microns and kept for one Dry at 60°C for an hour. Progesterone receptor detection in paraffin-fixed tissue sections is performed using a specific kit detection system.;Positive HER2 protein level in cancer cells. Timepoint: When the person definitely has breast cancer and the goal is to determine the severity of the person's disease. Method of measurement: Container/tube: formalin container for biopsied sample / paraffin blocks containing cancer sample, sample type: usually this test is done on biopsy sample taken for primary diagnosis and no second biopsy is required. The laboratory technique for determining the level of HER2 on the cell surface is immunohistochemistry.;The degree of malignancy of the breast mass. Timepoint: If the lump surgery is not possible at all, the histological method is used to determine the degree of malignancy of the breast lump. Method of measurement: The staging system most often used for breast cancer is the system established by the American Joint Committee on Cancer, in which | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactDr Iraj Abedi
Esfahan University of Medical Sciences
Outcome results
None listed