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Comparison of the effect of carbetocin with oxytocin in prevention of uterine atony after elective caesarean section

Comparison of the effect of carbetocin with oxytocin in prevention of uterine atony after elective caesarean section

Status
Recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20240129060839N1
Enrollment
100
Registered
2025-01-22
Start date
2024-01-22
Completion date
Unknown
Last updated
2025-02-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

uterine atony.

Interventions

Intervention 1: Intervention group: carbetocin. Intervention 2: Intervention group: Oxytocin.

Sponsors

Tehran University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
No minimum to 45 Years

Inclusion criteria

Inclusion criteria: Pregnant women referred to Bharlo Hospital with a gestational age of over 37 weeks who are candidates for elective cesarean section

Exclusion criteria

Exclusion criteria: Pregnant mothers over 45 years old Gestational age below 37 weeks Pregnant women who are candidates for emergency caesarean section Pregnant women with chronic blood pressure diseases Duration of surgery more than one hour Pregnant mothers with a history of fibroma and bleeding in a previous delivery Pregnant mothers with a history of placenta previa and placental accreta • Mothers with twins

Design outcomes

Primary

MeasureTime frame
Hemoglobin levels of people in the intervention process. Timepoint: Before cesarean section, after cesarean section, and in the recovery room after receiving blood or serum if needed. Method of measurement: laboratory.;Body Mass Index. Timepoint: When entering the study. Method of measurement: From dividing weight (kilograms) by height (meters) to the power of 2.;Gravid. Timepoint: When entering the study. Method of measurement: Case information and questions from the mother.;Mother's age. Timepoint: When entering the study. Method of measurement: Case information and questions from the mother.;Systolic blood pressure. Timepoint: Before cesarean section, after cesarean section, and in the recovery room after receiving blood or serum if needed. Method of measurement: Blood pressure monitor.;?Diastolic Blood pressure. Timepoint: Before cesarean section, after cesarean section, and in the recovery room after receiving blood or serum if needed. Method of measurement: Blood pressure monitor.;Heart rate. Timepoint: Before cesarean section, after cesarean section, and in the recovery room after receiving blood or serum if needed. Method of measurement: monitoring.;Nausea and vomiting. Timepoint: Before cesarean section, after cesarean section, and in the recovery room after receiving blood or serum if needed. Method of measurement: Monitoring.

Secondary

MeasureTime frame
Carbetocin. Timepoint: after cesarean section. Method of measurement: In intervention group 2, 100 micrograms of carbetocin diluted in 5 cc of distilled water was injected slowly over one minute.;Oxytocin. Timepoint: after cesarean section. Method of measurement: 20 units of oxytocin injected immediately after placental delivery.;. Timepoint: . Method of measurement: .;Oxytocin. Timepoint: after cesarean section. Method of measurement: 20 units of oxytocin injected immediately after placental delivery.;Need for blood transfusion. Timepoint: If needed and hemoglobin drops. Method of measurement: Laboratory.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactMohammad Ali Ahmadi

Tehran University of Medical Sciences

mohammad.a.ahmadi777@gmail.com+98 939 234 3598

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026