Helicobacter pylori infection. Helicobacter pylori [H.pylori] as the cause of diseases classified to other chapters
Conditions
Interventions
Intervention 1: Intervention group: Administration of amoxicillin 1000 mg every 12 hours, moxifloxacin 400 mg every 12 hours, and pantoprazole 40 mg every 12 hours for 10 days, followed by pantoprazol
Sponsors
Ahvaz University of Medical Sciences
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: Age above 18 years All patients with PUD, peptic ulcer, non-ulcer dyspepsia and intestinal metaplasia (based on pathology samples) underwent endoscopic evaluation and H. pylori positive confirmation by Rapid urease test (RUT). No previous treatment of H. pylori infection Patient consent to participate in the study
Exclusion criteria
Exclusion criteria: Unwillingness to participate in the study Taking antibiotics or non-steroidal anti-inflammatory drugs (NSAID) in the last 4 weeks Allergy to any of the study drugs A history of gastric surgery or the presence of a serious concurrent disease such as cancer Pregnant or lactating women
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Determination of positive or negative Helicobacter infection by fecal antigen test. Timepoint: Helicobacter test before and two weeks after treatment. Method of measurement: Helicobacter pylori fecal antigen. | — |
Secondary
| Measure | Time frame |
|---|---|
| Drug side effects. Timepoint: During treatment and two weeks after treatment. Method of measurement: Registration in the patient's self-report questionnaire.;Acceptance of medication. Timepoint: During treatment and two weeks after treatment. Method of measurement: Registration in the patient's self-report questionnaire. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactAmir hooshang bavarsad
Ahvaz University of Medical Sciences
Outcome results
None listed