Effects of skin electrical stimulation at acupuncture points on hemodynamics, pain, nausea and vomiting during anesthesia

Effects of skin electrical stimulation at acupuncture points PC6, ST36 and LI4 on hemodynamics, pain, nausea and vomiting during anesthesia in patients requiring elective laparoscopic cholecystectomy

Status

Recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20240123060780N4

Enrollment

Registered

2026-03-16

Start date

2026-04-02

Completion date

Unknown

Last updated

2026-06-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Pain. Acute pain, not elsewhere classified

Interventions

Intervention 1: Intervention group: Stimulation electrodes are placed bilaterally at the Hugo (LI4), Niguan (PC6), and Zusanli (ST36) acupuncture points and connected to an active electrical stimulati

Eligibility

Sex/Gender

Female

Age

25 Years to 60 Years

Inclusion criteria

Inclusion criteria: Female patients requiring elective laparoscopic cholecystectomy who have anesthesia risk levels 1 and 2 according to the American Society of Anesthesiologists (ASA) classification Reading literacy Healthy speech and vision abilities The skin in the area of ??electrical stimulation be healthy

Exclusion criteria

Exclusion criteria: Peripheral edema in the area of ??stimulation History of smoking or drug use Use of analgesic or anti-nausea and vomiting medications in the past 24 hours The patient's previous complicated surgical and anesthetic history at the time of the history taking. Pregnancy Breastfeeding Taking sedatives History of diabetes History of vascular disease Having pacemakers and implantable cardiac defibrillators

Design outcomes

Primary

Measure	Time frame
Heart rate. Timepoint: Heart rate is measured before and after laryngoscopy (insertion of the endotracheal tube), before and after removal of the endotracheal tube, and every 15 minutes during anesthesia. Method of measurement: Using patient-attached monitoring.;Systolic and diastolic blood pressure. Timepoint: Blood pressure is measured before and after laryngoscopy (insertion of the endotracheal tube), before and after removal of the endotracheal tube, and every 15 minutes during anesthesia. Method of measurement: Using patient-attached monitoring.;Pain. Timepoint: Postoperative pain is measured during recovery and at 6, 12, and 24 hours after surgery. Method of measurement: Based on visual analogue scale (VAS).;Severity of postoperative nausea and vomiting. Timepoint: Within 24 hours after surgery. Method of measurement: It is performed using the Simplified PONV Impact Scale tool.;Amount of analgesia taken. Timepoint: Within 24 hours after surgery. Method of measurement: Dosage in milligrams according recording in patient file.	—

Measure

Time frame

Heart rate. Timepoint: Heart rate is measured before and after laryngoscopy (insertion of the endotracheal tube), before and after removal of the endotracheal tube, and every 15 minutes during anesthesia. Method of measurement: Using patient-attached monitoring.;Systolic and diastolic blood pressure. Timepoint: Blood pressure is measured before and after laryngoscopy (insertion of the endotracheal tube), before and after removal of the endotracheal tube, and every 15 minutes during anesthesia. Method of measurement: Using patient-attached monitoring.;Pain. Timepoint: Postoperative pain is measured during recovery and at 6, 12, and 24 hours after surgery. Method of measurement: Based on visual analogue scale (VAS).;Severity of postoperative nausea and vomiting. Timepoint: Within 24 hours after surgery. Method of measurement: It is performed using the Simplified PONV Impact Scale tool.;Amount of analgesia taken. Timepoint: Within 24 hours after surgery. Method of measurement: Dosage in milligrams according recording in patient file.

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Countries

Iran (Islamic Republic of)

Contacts

Public ContactJavad Aminisaman

Kermanshah University of Medical Sciences

aminisamanj99@gmail.com+98 83 3427 4618

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Jun 11, 2026