Effect of Platelet-Rich Plasma Injection on Rotator Cuff Tear Repair

Investigating the amount of rotator cuff tear repair by injecting platelet-rich plasma under ultrasound guidance

Status

Recruiting

Phases

Phase 1

Study type

Interventional

Source

IRCT

Registry ID

IRCT20240123060779N1

Enrollment

Registered

2024-03-20

Start date

2024-04-03

Completion date

Unknown

Last updated

2024-05-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Rotator cuff tear. Unspecified rotator cuff tear or rupture, not specified as traumatic

Interventions

Intervention group: In this clinical trial study, the intervention group consists of patients with rotator cuff tears who undergo platelet-rich plasma (PRP) injection. The PRP preparation process invo

Eligibility

Sex/Gender

All

Age

18 Years to 80 Years

Inclusion criteria

Inclusion criteria: Age range: 18 to 80 years old Initial tear Traumatic or degenerative tear with less than 50% thickness Willingness to participate in the study

Exclusion criteria

Exclusion criteria: Secondary rotator cuff tear due to fracture or dislocation Presence of dislocation during the study period Rotator cuff tears that have previously undergone surgical repair or corrective arthroscopy Diseases associated with upper limb pain such as arthritis, infection, carpal tunnel syndrome, cervical neuropathy Localized malignancy Systemic disorders such as uncontrolled diabetes and hypothyroidism, pregnancy, platelet count less than 125,000 Having definitive disability or inability to attend for follow-up after injection

Design outcomes

Primary

Measure	Time frame
Determination of rotator cuff tear repair extent based on changes in percentage of tear. Timepoint: Before intervention and at 2 months and 6 months post-initiation of platelet-rich plasma injection. Method of measurement: Ultrasound imaging.;Determination of rotator cuff tear repair extent based on changes in mediolateral tear length. Timepoint: Before intervention and at 2 months and 6 months post-initiation of platelet-rich plasma injection. Method of measurement: Ultrasound imaging.;Determination of rotator cuff tear repair extent based on changes in pain level. Timepoint: Before intervention and at 2 months and 6 months post-initiation of platelet-rich plasma injection. Method of measurement: Ultrasound imaging.;Determination of rotator cuff tear repair extent based on changes in shoulder range of motion. Timepoint: Before intervention and at 2 months and 6 months post-initiation of platelet-rich plasma injection. Method of measurement: Ultrasound imaging.	—

Measure

Time frame

Determination of rotator cuff tear repair extent based on changes in percentage of tear. Timepoint: Before intervention and at 2 months and 6 months post-initiation of platelet-rich plasma injection. Method of measurement: Ultrasound imaging.;Determination of rotator cuff tear repair extent based on changes in mediolateral tear length. Timepoint: Before intervention and at 2 months and 6 months post-initiation of platelet-rich plasma injection. Method of measurement: Ultrasound imaging.;Determination of rotator cuff tear repair extent based on changes in pain level. Timepoint: Before intervention and at 2 months and 6 months post-initiation of platelet-rich plasma injection. Method of measurement: Ultrasound imaging.;Determination of rotator cuff tear repair extent based on changes in shoulder range of motion. Timepoint: Before intervention and at 2 months and 6 months post-initiation of platelet-rich plasma injection. Method of measurement: Ultrasound imaging.

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Countries

Iran (Islamic Republic of)

Contacts

Public ContactFarnood Rajabzadeh

Mashhad University of Medical Sciences

f.rajabzadeh@mshdiau.ac.ir+98 51 3844 7207

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026