Effect of intrauterine injection of platelet-rich plasma on pregnancy outcome

Comparing the effect of intrauterine injection of platelet-rich plasma on pregnancy outcome in IVF candidate women with recurrent implantation failure and thin endometrium

Status

Recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20240119060732N1

Enrollment

Registered

2024-01-28

Start date

2024-02-29

Completion date

Unknown

Last updated

2024-03-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Female infertility of uterine origin. Female infertility of uterine origin

Interventions

Intervention 1: Intervention group: 24 to 48 hours before the embryo transfer, 5 cc of platelet-rich plasma, which is prepared from the person's peripheral blood, is poured into the uterus using an in

Eligibility

Sex/Gender

Female

Age

20 Years to 38 Years

Inclusion criteria

Inclusion criteria: Age 20 to 38 years Body mass index below 30 Patients with embryo quality A or B Endometrial thickness less than 7 mm despite receiving hormonal treatment With a history of IVF failure

Exclusion criteria

Exclusion criteria: Patients with diabetes Use of immune system suppressing drugs Patients with malignancy Uterine myomatosis or adenomyosis or hydrosalpingus Endometriosis stage 4 The presence of acute pelvic infection The presence of blood or platelet disorders

Design outcomes

Primary

Measure	Time frame
Clinical pregnancy. Timepoint: Once, six weeks after fetal transfer. Method of measurement: Ultrasound.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactFiroozeh Akbari Asbagh

Tehran University of Medical Sciences

fasbagh_md@yahoo.com+98 21 4216 0852

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026