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Comparison of the effect of inhaled salbutamol- ipratropium solution with and without inhaled furosemide solution on signs and symptoms, pulmonary function tests and inflammatory biomarkers in patients with exacerbation of chronic obstructive pulmonary disease.

Comparison of the effect of inhaled salbutamol- ipratropium solution with and without inhaled furosemide solution on signs and symptoms, pulmonary function tests and inflammatory biomarkers in patients with exacerbation of chronic obstructive pulmonary disease.

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20240118060726N1
Enrollment
92
Registered
2024-06-08
Start date
2024-02-20
Completion date
Unknown
Last updated
2024-06-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Chronic Obstructive Pulmonary Disease Exacerbations. Chronic obstructive pulmonary disease with (acute) exacerbation

Interventions

Intervention 1: Intervention group: Receiving routine services and prescribing 2.5 cc of salbutamol-ipratropium inhalation solution with a dose of 2.5 mg of salbutamol, 0.5 mg of ipratropium and 20 mg

Sponsors

Shahid Beheshti University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
20 Years to 65 Years

Inclusion criteria

Inclusion criteria: Definite diagnosis of exacerbation COPD disease Age range of 20-65 years Stable vital signs Controlled and constant medication regimen during the study

Exclusion criteria

Exclusion criteria: Moderate to severe heart failure Digestive problems such as severe nausea and vomiting Cancers of the respiratory tract Chronic kidney or liver disease Surgery of the respiratory system over the past year Pregnancy and breastfeeding Allergy to sulfated drugs Withdrawal from participating

Design outcomes

Primary

MeasureTime frame
Severity of symptoms of cough, sputum, shortness of breath, restriction of daily activities, insomnia, premature fatigue during activity. Timepoint: 5 days. Method of measurement: CAT Scoring.;Duration of symptoms (disease). Timepoint: 5 days. Method of measurement: Questionnaire.;Chronic Obstructive Pulmonary Disease Exacerbation. Timepoint: 5 days. Method of measurement: Examination and radiology.;Number of years since diagnosis. Timepoint: 5 days. Method of measurement: Questionnaire.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactMahdi Behi

Shahid Beheshti University of Medical Sciences

daaroo85@yahoo.com+98 21 2243 9969

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026