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Investigating the effect of Shirazi thyme essential oil on the clinical symptoms of patients with gastroesophageal reflux

The effect of Shirazi thyme essential oil on the clinical symptoms of patients with gastroesophageal reflux disease

Status
Recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20240116060709N1
Enrollment
70
Registered
2024-02-21
Start date
2024-02-24
Completion date
Unknown
Last updated
2024-03-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Gastroesophageal reflux disease. Gastro-esophageal reflux disease without esophagitis

Interventions

Intervention 1: Intervention group: After completing the demographic questionnaire and gastric reflux disease questionnaire, one gastrolith capsule (containing 20 mg of Shirazi thyme essential oil, ma

Sponsors

Gonabad University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
20 Years to 60 Years

Inclusion criteria

Inclusion criteria: Willingness to attend the study Patients with second grade reflux severity (patients who were not able to resolve their symptoms with lifestyle changes alone) Age 20 to 60 years Absence of pregnancy and breastfeeding Absence of allergy to thyme Not having diabetes No previous upper gastrointestinal surgery Absence of positive and clinically significant gastrointestinal bleeding in the last three months Absence of proven diseases such as: bleeding disorder, Barrett's Esophagus,esophageal varices, duodenal/stomach ulcer and upper gastrointestinal tract malignancy Able to read, understand and complete the questionnaire

Exclusion criteria

Exclusion criteria: Reluctance to continue research Hospitalization during the study Not using gastrolith capsules for more than 5 days

Design outcomes

Primary

MeasureTime frame
Percentage of people with second-degree gastroesophageal reflux (patients who were not able to resolve their symptoms only by lifestyle changes). Timepoint: Before the intervention and 45 days after the intervention. Method of measurement: Reflux disease questionnaire.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactBenyamin Borhani

Gonabad University of Medical Sciences

benyaminborhani72@gmail.com+98 51 5722 3513

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026