Major Depressive Disorder (MDD).
Conditions
Interventions
Intervention 1: Intervention group 1: Cognitive rehabilitation. Intervention 2: Intervention group 2: Cognitive Behavioral Therapy (CBT).
Sponsors
Iran University of Medical Sciences
Eligibility
Sex/Gender
All
Age
55 Years to No maximum
Inclusion criteria
Inclusion criteria: Diagnosis of major depression by semi-structured SCID interview A score higher than 6 in the Geriatric Depression Scale (GDS) Receiving antidepressants (SSRI) At least 3 weeks have passed since the start of drug treatment At least 55 years old Education above seventh grade
Exclusion criteria
Exclusion criteria: Major and minor cognitive impairment based on DSM-5 A score lower than 26 in the MoCA Having psychotic disorders or brain damage
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Depression symptoms. Timepoint: In three stages including: the beginning of the study (before the start of the intervention), immediately after the end of the intervention, 3 months after the end of the intervention. Method of measurement: Depression criteria of DSM-5 (SCID), Geriatric Depression Scale (GDS).;Quality of life. Timepoint: In three stages including: the beginning of the study (before the start of the intervention), immediately after the end of the intervention, 3 months after the end of the intervention. Method of measurement: The World Health Organization Quality of Life Persian questioner. | — |
Secondary
| Measure | Time frame |
|---|---|
| Executive function. Timepoint: In three stages including: the beginning of the study (before the start of the intervention), immediately after the end of the intervention, 3 months after the end of the intervention. Method of measurement: Trial making test, Verbal fluency.;Attention and consentration. Timepoint: In three stages including: the beginning of the study (before the start of the intervention), immediately after the end of the intervention, 3 months after the end of the intervention. Method of measurement: Digit span (DS).;Information processing speed. Timepoint: In three stages including: the beginning of the study (before the start of the intervention), immediately after the end of the intervention, 3 months after the end of the intervention. Method of measurement: Symbol Digit Modality Test (SDMT).;Verbal memory. Timepoint: In three stages including: the beginning of the study (before the start of the intervention), immediately after the end of the intervention, 3 months after the end of the intervention. Method of measurement: Logical Memory (LM). | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactNafee Rasouli
Iran University of Medical Sciences
Outcome results
None listed