Major depression. Major depressive disorder, recurrent severe without psychotic features
Conditions
Interventions
Intervention 1: Intervention group: Cognitive behavioral therapy is performed in 12-16 sessions (45-60 minutes) according to the protocol (Leahy, 2012) twice a week. After the initial assessment and i
Sponsors
Islamic Azad University
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: All major depression patients Subjects had to show symptoms of major depressive disorder confirmed by a psychiatrist according to the HDRS (21). The participants had to complete a written consent form and were not exposed to any psychological or complementary treatment for at least one month before entering the study. Carrying metal or other electrical devices on the head or having wounds and scratches on the scalp. Absent contraindications to tDCS, such as metal in the head or medical devices implanted in the brain, experience at least Three AHs per week Age: 18 to 65 years old
Exclusion criteria
Exclusion criteria: Risk of suicide, History of epilepsy and seizures Presence of an electrical or metal object in the body Presence of any neurological disease that affects the central nervous system (such as Parkinson's) Pregnancy Co-occurring bipolar disorder Psychosis
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The individual's score on Hamilton Depression Rating Scale (HDRS). Timepoint: Measuring the severity of depressive symptoms before the intervention, immediately after the intervention, and one month after the intervention as a follow-up. Method of measurement: Hamiltonian measurement test.;Wisconsin Cognitive Flexibility Test (WCST) score. Timepoint: Measuring the individual's WCST score before the intervention, immediately after the intervention, and one month after the intervention as a follow-up. Method of measurement: Wisconsin Cognitive Task (WCST) by Sina Software.;Working memory score in the N-BACK test. Timepoint: Measuring the individual's N-BACK score before the intervention, immediately after the intervention, and one month after the intervention as a follow-up. Method of measurement: N-BACK working memory cognitive task by Sina Software.;Cognitive selective attention score in the simple Stroop test. Timepoint: Measuring the individual's score on the simple stroop task before the intervention, immediately after the intervention, and one month after the intervention as a follow-up. Method of measurement: Simple Stroop cognitive attention and concentration task by Sina Company software.;Cognitive attention inhibition score in the GONOGO test. Timepoint: Measuring the individual's score on the GONOGO task before the intervention, immediately after the intervention, and one month after the intervention as a follow-up. Method of measurement: Cognitive task of attention inhibition by Sina Company software.;The individual's score on the beck Depression Inventory(BDI). Timepoint: Measuring the severity of depressive symptoms before the intervention, immediately after the intervention, and one month after the intervention as a follow-up. Method of measurement: he individual's score on Beck Depression Inventory (BDI).;The individual's score on the Montgomery-Aasberg Depression Rating Scale (MADRS). Timepoint: Measuring the severity of depressive symptoms before the | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactAlireza Atabakhsh
Islamic Azad University
Outcome results
None listed