Evaluation of The effect of mini gastric bypass bariatric surgery on metabolic syndrome and its ultrasonography and vascular factors

Evaluation of the effect of Mini-Gastric Bypass as Bariatric surgery on sonographic factors (fatty liver, liver fibrosis, visceral fat) and vascular endothelial indices such as Flow-Mediated Dilation (FMD), Carotid Intima Media Thickness (CIMT) and atherosclerotic plaques in short term in patients with metabolic syndrome

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

IRCT

Registry ID

IRCT20240105060617N1

Enrollment

Registered

2024-07-03

Start date

2024-09-22

Completion date

Unknown

Last updated

2024-07-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Mini-Gastric Bypass surgery (a bariatric surgery).

Interventions

Intervention group: This study has only one group of obese patients who undergo mini-bypass surgery (one of the types of bariatric surgery) and are evaluated before and after it. The surgery consists

Second, a 200 cm jejunal bypass with a single gastro-jejunostomy (GJ) anastomosis, which leads to significant (fat)malabsorption..

Eligibility

Sex/Gender

All

Age

30 Years to 55 Years

Inclusion criteria

Inclusion criteria: Age 30 to 55 years Body mass index (BMI) over 35 Candidate for Bariatric surgery based on scientific indication

Exclusion criteria

Exclusion criteria: Have a history of heart disease Have a history of diabetes Have a history of hypertension

Design outcomes

Primary

Measure	Time frame
Fatty liver grading in ultrasound. Timepoint: Once at the time of the visit (before surgery) and once 4 months after surgery. Method of measurement: liver ultrasound and report in grade 1, 2 ,3.;Liver fibrosis based on liver elastography. Timepoint: One at visit time (before surgery) and once 4 months after surgery. Method of measurement: with liver ultrasound and quantitative report.;Abdominal visceral fat percentage. Timepoint: Once at the time of visit(before surgery) and once 4 months after surgery. Method of measurement: Based on abdominal ultrasonography and report its quantitative thickness.;Carotid intima media thickness (CMIT). Timepoint: Once at the time of visit(before surgery) and once 4 months after surgery. Method of measurement: with cervical carotid artery sonography and report in millimeters.;Flow-mediated dilation (FMD). Timepoint: Once at the time of visit (before surgery) and once 4 months after surgery. Method of measurement: With Peripheral vascular ultrasound and report in percentage.;Atherosclerotic plaque thickness (Focal increase in arterial wall width) in carotid arteries. Timepoint: Once at the time of visit(before surgery) and once 4 months after surgery. Method of measurement: With cervical carotid artery sonography and report in millimeters.	—

Measure

Time frame

Fatty liver grading in ultrasound. Timepoint: Once at the time of the visit (before surgery) and once 4 months after surgery. Method of measurement: liver ultrasound and report in grade 1, 2 ,3.;Liver fibrosis based on liver elastography. Timepoint: One at visit time (before surgery) and once 4 months after surgery. Method of measurement: with liver ultrasound and quantitative report.;Abdominal visceral fat percentage. Timepoint: Once at the time of visit(before surgery) and once 4 months after surgery. Method of measurement: Based on abdominal ultrasonography and report its quantitative thickness.;Carotid intima media thickness (CMIT). Timepoint: Once at the time of visit(before surgery) and once 4 months after surgery. Method of measurement: with cervical carotid artery sonography and report in millimeters.;Flow-mediated dilation (FMD). Timepoint: Once at the time of visit (before surgery) and once 4 months after surgery. Method of measurement: With Peripheral vascular ultrasound and report in percentage.;Atherosclerotic plaque thickness (Focal increase in arterial wall width) in carotid arteries. Timepoint: Once at the time of visit(before surgery) and once 4 months after surgery. Method of measurement: With cervical carotid artery sonography and report in millimeters.

—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactMohammad Mersad Mansouri Tehrani

Tehran University of Medical Sciences

mersad.mansouri@sbmu.ac.ir+98 21 2243 9701

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026