Comparison of the Effectiveness of Pumpkin Cream and Estrogen Vaginal Cream on Symptoms of vaginal Atrophy in Postmenopausal Women

Status

Recruiting

Phases

Phase 2

Study type

Interventional

Source

IRCT

Registry ID

IRCT20240104060610N1

Enrollment

100

Registered

2024-04-03

Start date

2024-04-20

Completion date

Unknown

Last updated

2024-05-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Menopause. Menopausal and other perimenopausal disorders

Interventions

Intervention 1: Intervention group: 50 postmenopausal women aged 50 to 70 years with a BMI of 20-25, who have been at least one year past menopause and have no history of any disease, and are referred

endometrial thickness will be measured by ultrasound before and 8 weeks after treatment by assistant. Intervention 2: Control group: 50 postmenopausal women aged 50 to 70 years with a BMI of 20-25, w

endom

Eligibility

Sex/Gender

Female

Age

50 Years to 70 Years

Inclusion criteria

Inclusion criteria: Having Informed and Written Consent to Participate in the Study Absence of Medical Disease Age 50 to 70 years At Lest 1 Year Has Passed since Menopaus

Exclusion criteria

Exclusion criteria: Lack of Informed and Written Consent to Participate in the Study Having Medical Disease Age Less than 50 Years Age older than 70 Years

Design outcomes

Primary

Measure	Time frame
Vaginal Maturation Index. Timepoint: Evaluation of Vaginal Maturity Index at the Beginning of the Study and 8 Weeks after Using Vaginal cream. Method of measurement: Vaginal Smear.;Vaginal Itching. Timepoint: Evaluation of Vaginal Itching at the Beginning of the Study and 8 Weeks after Using Vaginal cream. Method of measurement: 4_Point Likert Scale Questionnaire.;Vaginal Burning. Timepoint: Evaluation of Vaginal Burning at the Beginning of the Study and 8 Weeks after Using Vaginal cream. Method of measurement: 4_Point Likert Scale Questionnaire.;Vaginal Dryness. Timepoint: Evaluation of Vaginal Dryness at the Beginning of the Study and 8 Weeks after Using Vaginal cream. Method of measurement: 4_Point Likert Scale Questionnaire.;Dyspareunia. Timepoint: Evaluation of Dyspareunia at the Beginning of the Study and 8 Weeks after Using Vaginal cream. Method of measurement: 4_Point Likert Scale Questionnaire.;Endometrial Thickness. Timepoint: Evaluation of Endometrial Thickness at the Beginning of the Study and 8 Weeks after Using Vaginal cream. Method of measurement: Trans Vaginal Ultrasound.	—

Measure

Time frame

Vaginal Maturation Index. Timepoint: Evaluation of Vaginal Maturity Index at the Beginning of the Study and 8 Weeks after Using Vaginal cream. Method of measurement: Vaginal Smear.;Vaginal Itching. Timepoint: Evaluation of Vaginal Itching at the Beginning of the Study and 8 Weeks after Using Vaginal cream. Method of measurement: 4_Point Likert Scale Questionnaire.;Vaginal Burning. Timepoint: Evaluation of Vaginal Burning at the Beginning of the Study and 8 Weeks after Using Vaginal cream. Method of measurement: 4_Point Likert Scale Questionnaire.;Vaginal Dryness. Timepoint: Evaluation of Vaginal Dryness at the Beginning of the Study and 8 Weeks after Using Vaginal cream. Method of measurement: 4_Point Likert Scale Questionnaire.;Dyspareunia. Timepoint: Evaluation of Dyspareunia at the Beginning of the Study and 8 Weeks after Using Vaginal cream. Method of measurement: 4_Point Likert Scale Questionnaire.;Endometrial Thickness. Timepoint: Evaluation of Endometrial Thickness at the Beginning of the Study and 8 Weeks after Using Vaginal cream. Method of measurement: Trans Vaginal Ultrasound.

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Countries

Iran (Islamic Republic of)

Contacts

Public ContactNasrin Rezaee

Shiraz University of Medical Sciences

nasrinrezaee123456@gmail.com+98 71 3612 8258

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026