Diminished Ovarian Reserve(DOR). Ovarian dysfunction, unspecified
Conditions
Interventions
Intervention 1: Intervention group: Injection of 1 ml of autologous PRP in 1 step into the ovaries of DOR patients under mild anesthesia with ultrasound guidance. Intervention 2: Intervention group:
Sponsors
Kerman University of Medical Sciences
Eligibility
Sex/Gender
Female
Age
20 Years to 45 Years
Inclusion criteria
Inclusion criteria: Women between 20 and 45 years old Having poor or diminished ovarian reserve and having one of the criteria for poor ovarian response, which are: total number of Antral Follicles Count in both ovaries 7 or less on vaginal ultrasound, AMH less than 1.1 ng/ml, history of IVF with 3 or fewer eggs Reading and signing the informed consent form
Exclusion criteria
Exclusion criteria: Pregnancy History or current IgA deficiency History of surgery leading to pelvic adhesions Taking anticoagulant medications Mental illness with dependence on drug use Chronic malignancies or chronic pelvic pain Infertility due to severe male factor Drug addiction Endometriosis and abnormal uterine shape observed in hysterosalpingogram Failure to sign the informed consent form
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Anti Mullerian Hormone. Timepoint: before injection and 2, 6 and 14 weeks after injection. Method of measurement: ELISA KIT.;Antral Follicle Count(AFC). Timepoint: before injection and 2, 6 and 14 weeks after injection. Method of measurement: Vaginal ultrasound. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactManizheh Habibpour
Mazandaran University of Medical Sciences
Outcome results
None listed