Dry eye disease / Rheumatoid arthritis. Dry eye syndrome
Conditions
Interventions
Intervention 1: Intervention group: 30 patients will be under treatment of punctal occlusion with plasma procedure in addition to their previous medications (artificial tears, lubricant eye gel, and w
Sponsors
Vision health research center
Eligibility
Sex/Gender
All
Age
20 Years to 70 Years
Inclusion criteria
Inclusion criteria: Coincidence of having dry eye disease and rheumatoid arthritis At least one of these symptoms must be present in one eye: redness, burning sensation, foreign body sensation, discomfort on the surface of the eye, or visual fatigue. The possibility of attending all treatment sessions and cooperating until the end of the project
Exclusion criteria
Exclusion criteria: Having a history of any surgical intervention for the treatment of dry eye Having any kind of eye surgery in the last six months Simultaneous enrollment in other interventional clinical studies Patients with active fungal, bacterial, or viral keratitis, or conjunctival edema Pregnant or breastfeeding women Refusing to sign the informed consent form for participation in the study
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Tear meniscus height. Timepoint: Before the start of the intervention, 3 to 6 months after the last treatment session. Method of measurement: Tear meniscus height will be measured in all visit sessions using Slit-lamp.;Schirmer test. Timepoint: Before the start of the intervention, 3 to 6 months after the last treatment session. Method of measurement: The produced amount of tear in 5minutes will be measured using the schirmer kit.;Tear breakup time. Timepoint: Before the start of the intervention, 3 to 6 months after the last treatment session. Method of measurement: The tear breakup time will be measured using Slit-lamp and Fluorescein staining.;Dry eye questionnaire. Timepoint: Before the start of the intervention, 3 to 6 months after the last treatment session. Method of measurement: the Ocular Surface Disease Index questionnaire will be filled by patients.;Punctal depth. Timepoint: Before the start of the intervention, 3 to 6 months after the last treatment session. Method of measurement: Punctal depth will be measured using Optical Coherence Tomography (OCT).;Outer Punctal Diameter (OPD). Timepoint: Before the start of the intervention, 3 to 6 months after the last treatment session. Method of measurement: Outer Punctal Diameter (OPD) will be measured using Optical Coherence Tomography (OCT).;The outer punctal diameter vertically (OPDV). Timepoint: Before the start of the intervention, 3 to 6 months after the last treatment session. Method of measurement: The outer punctal diameter vertically (OPDV) will be measured using the CSO slit-lamp.;Outer punctal diameter horizontally (OPDH). Timepoint: Before the start of the intervention, 3 to 6 months after the last treatment session. Method of measurement: The outer punctal diameter horizontally (OPDH) will be measured using the CSO slit-lamp.;The inner punctal diameter horizontally (IPDH). Timepoint: Before the start of the intervention, 3 to 6 months after the last treatment session. Method of measurement: The inn | — |
Secondary
| Measure | Time frame |
|---|---|
| Uncorrected Visual Acuity (UCVA). Timepoint: Before the start of the intervention, 3 to 6 months after the last treatment session. Method of measurement: Measuring each person's clarity and sharpness of vision without using corrective lenses.;Best Corrected Visual Acuity (BCVA). Timepoint: Before the start of the intervention, 3 to 6 months after the last treatment session. Method of measurement: Achieving the best vision for each individual using corrective lenses.;Intra Ocular Pressure (IOP). Timepoint: Before the start of the intervention, 3 to 6 months after the last treatment session. Method of measurement: IOP will be measured by a rebound tonometer (iCare Finland Oy, Vantaa, Finland). | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactFarhad Nejat
Vision health research center
Outcome results
None listed