Effect of traditional preparation rectal suppository in treatment of hemorrhoids

Effect of a traditional preparation rectal suppository from Commiphora mukul (Hook. Ex Stocks) Engl. And Allium porrum L. on hemorrhoids in comparison with conventional anti-hemorrhoid suppository: A double-blind controlled trial

Status

Recruiting

Phases

Unknown

Study type

Interventional

Source

IRCT

Registry ID

IRCT20231224060516N1

Enrollment

Registered

2024-01-23

Start date

2024-01-20

Completion date

Unknown

Last updated

2024-03-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Hemorrhoid. Hemorrhoids and perianal venous thrombosis

Interventions

Intervention 1: The intervention group: 28 rectal suppositories containing Commiphora mukul (Hook. Ex Stocks) Engl. and Allium porrum L. made by the researcher, BID for two weeks. Intervention 2: The

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Suffering from hemorrhoids based on the diagnosis of a general surgeon that does not require emergency surgery The patient must sign a consent form and cooperate during the study Has not been treated for hemorrhoids in the past month

Exclusion criteria

Exclusion criteria: Fourth-degree hemorrhoids Pregnancy Breastfeeding Diabetes Portal hypertension Various known coagulopathy Liver and kidney failure Inflammatory bowel diseases Perianal fissure Anal fistula Taking medication for hemorrhoids in the last 1 month History Hemorrhoid surgery in the last 6 months Thrombosed external hemorrhoid Strangulated internal hemorrhoid Anal abscess History of perianal surgery Mucosal prolapse Cancer and other malignancies

Design outcomes

Primary

Measure	Time frame
Pain. Timepoint: Before intervention, 2 weeks after initiation of intervention. Method of measurement: Colo-Rectal Evaluation of Clinical Therapeutics Scale questionnaire (CORECTS).;Itching. Timepoint: Before intervention, 2 weeks after initiation of intervention. Method of measurement: Colo-Rectal Evaluation of Clinical Therapeutics Scale questionnaire (CORECTS).;Swelling. Timepoint: Before intervention, 2 weeks after initiation of intervention. Method of measurement: Colo-Rectal Evaluation of Clinical Therapeutics Scale questionnaire (CORECTS).;Bleeding. Timepoint: Before intervention, 2 weeks after initiation of intervention. Method of measurement: Colo-Rectal Evaluation of Clinical Therapeutics Scale questionnaire (CORECTS).	—

Measure

Time frame

Pain. Timepoint: Before intervention, 2 weeks after initiation of intervention. Method of measurement: Colo-Rectal Evaluation of Clinical Therapeutics Scale questionnaire (CORECTS).;Itching. Timepoint: Before intervention, 2 weeks after initiation of intervention. Method of measurement: Colo-Rectal Evaluation of Clinical Therapeutics Scale questionnaire (CORECTS).;Swelling. Timepoint: Before intervention, 2 weeks after initiation of intervention. Method of measurement: Colo-Rectal Evaluation of Clinical Therapeutics Scale questionnaire (CORECTS).;Bleeding. Timepoint: Before intervention, 2 weeks after initiation of intervention. Method of measurement: Colo-Rectal Evaluation of Clinical Therapeutics Scale questionnaire (CORECTS).

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Countries

Iran (Islamic Republic of)

Contacts

Public ContactMotahare Nayebzadeh

Faculty of pharmacy

motaharenayeb@sums.ac.ir+98 71 3235 5677

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026