Effects of etomidate, propofol and etomidate combined with propofol on hemodynamic changes in high blood pressure patients

Investigating the effects of etomidate, propofol and etomidate combined with propofol injections on hemodynamic changes in high blood pressure patients who are candidates for general anesthesia

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20231222060494N1

Enrollment

150

Registered

2024-01-07

Start date

2024-02-20

Completion date

Unknown

Last updated

2024-01-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Hemodynamic status. Elevated blood-pressure reading, without diagnosis of hypertension

Interventions

Intervention 1: Intervention group: The group receiving propofol 1.5-2 mg/kg (Tehran shimi Co). Intervention 2: Intervention group: The group receiving etomidate 0 3 mg/kg (Aboreihan Co). Intervention

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Inclusion criteria

Inclusion criteria: Patients with blood pressure between 140/80 and 170/90 are candidates for abdominal surgery

Exclusion criteria

Exclusion criteria: Patients with hemodynamic disorder who need therapeutic fluid and vasopressor.

Design outcomes

Primary

Measure	Time frame
Blood pressure. Timepoint: The first, fifth and tenth minutes after induction. Method of measurement: Vital signs monitoring device.	—

Secondary

Measure	Time frame
Pulse rate. Timepoint: The first, fifth and tenth minutes after induction. Method of measurement: Vital signs monitoring device.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactSomayye Najafpour

Ardabil University of Medical Sciences

drsomayye@gmail.com+98 45 3323 2520

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026