Investigating the agreement of hypomagnesemia diagnosis based on three methods of serum , urine and red blood cells magnesium

Investigating the agreement of hypomagnesemia diagnosis based on three methods of serum , urine and red blood cells magnesium in intensive care unit : prospective trial

Status

Recruiting

Phases

Phase 2

Study type

Interventional

Source

IRCT

Registry ID

IRCT20231220060484N3

Enrollment

Registered

2024-04-18

Start date

2024-05-09

Completion date

Unknown

Last updated

2024-05-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Condition 1: Serum Magnesium. Condition 2: Red Blood Cell Magnesium. Condition 3: Urine Magnesium. Abnormal level of blood mineral Abnormal level of blood mineral Abnormal level of blood mineral

Interventions

Intervention group: 7.5 grams of magnesium sulfate in 1000 cc of isotonic saline during 8 hours and at a rate of 125 cc per hour as intravenous injection.

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Inclusion criteria

Inclusion criteria: At least 72 hours of placement in ICU The patient's lack of hypermagnesium Not receiving magnesium supplement at least in the past 72 hours Absence of pregnancy and breastfeeding

Exclusion criteria

Exclusion criteria: The presence of kidney dysfunction (serum creatinine above 1.5 mg per dL) Heart rate less than 60 per minute Severe metabolic disorder The patient is treated with diuretic drugs Coagulopathy

Design outcomes

Primary

Measure	Time frame
Investigation of serum magnesium. Timepoint: At the beginning of the study. Method of measurement: End point colorimetric.;Investigation of red blood cell magnesium. Timepoint: At the beginning of the study. Method of measurement: Using the device ICP-OES.;Investigation of urine magnesium. Timepoint: At the end of collecting 24 hour urine. Method of measurement: By using the method MLT.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactAmirhossein Ghanbarzamani

Islamic Azad University

amirh.ghzamani@gmail.com+98 21 2264 0056

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026