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Investigating and comparing the severity and prevalence of ventilator-induced pneumonia in patients taking famotidine and pantoprazole in the intensive care unit

Investigating and comparing the severity and prevalence of ventilator-induced pneumonia in patients taking famotidine and pantoprazole in the intensive care unit

Status
Recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20231220060484N2
Enrollment
124
Registered
2024-04-09
Start date
2024-05-11
Completion date
Unknown
Last updated
2024-05-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

ventilator-induced pneumonia. ventilator-associated pneumonia

Interventions

Intervention group: One group will be treated with stress ulcer prophylaxis regimen with intravenous pantoprazole 40 mg daily and the second group will be treated with stress ulcer prophylaxis regimen

Sponsors

Islamic Azad University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 80 Years

Inclusion criteria

Inclusion criteria: The inclusion criteria for the study of patients include the use of patients aged 18 to 80 years in intensive care units who have mechanical ventilation for at least 48 hours.

Exclusion criteria

Exclusion criteria: Patients with active pulmonary infection, patients with immunosuppression, patients with liver problems, renal problems (high creatinine levels), people with a history of sensitivity, and those with active gastrointestinal bleeding will not be included.

Design outcomes

Primary

MeasureTime frame
Pneumonia incidence is measured by the occurrence of infection or its non-occurrence. Timepoint: Investigating the occurrence of pneumonia after 48 hours of hospitalization. Method of measurement: Qualitative measurement with CT scan or Chest X-ray criteria / Quantitative measurement with CPIS criteria.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactSanaz Omidi

Islamic Azad University

omidi.san@gmail.com+98 21 2264 0051

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026