Investigating the Effect of Ursodeoxycholic acid and Phototherapy against Phototherapy alone in Reducing the Plasma Level of Bilirubin in Infants

Status

Recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20231220060483N1

Enrollment

200

Registered

2024-03-14

Start date

2024-03-20

Completion date

Unknown

Last updated

2024-05-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Hyperbilirubinemia. Other disorders of bilirubin metabolism

Interventions

Intervention 1: Intervention group: In the intervention group, along with phototherapy, ursodeoxycholic acid drops of 15 mg/kg per day divided into three times and for two days are prescribed. (Orsode

Eligibility

Sex/Gender

All

Age

2 Days to 14 Days

Inclusion criteria

Inclusion criteria: 1. GA> 37 W No Congenital abnormality No Asphyxia No congenital heart disease No need for oxygen Birth weight more than 2500 The age of the baby is between 2 and 14 days No sepsis symptoms

Exclusion criteria

Exclusion criteria: Lack of parental consent A baby admitted to the NICU Initial serum bilirubin less than 15 g/dL

Design outcomes

Primary

Measure	Time frame
Serum bilirubin level at different hours. Timepoint: At the beginning of the baby's hospitalization and at 6, 24 and 36 hours after the start of treatment. Method of measurement: A blood sample is taken and the answer is announced by the laboratory.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactElahe Motamedi Nasab

Shahid Beheshti University of Medical Sciences

Elahemotamedi67@gmail.com+98 21 2222 7021

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026