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Comparison of ketorolac and haloperidol in headache

Investigating and comparing the effect of ketorolac 30 mg intravenous and haloperidol 5 mg intravenous in reducing the intensity of primary headache in patients with the chief complaint of headache at the emergency department of Sina Hospital.

Status
Recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20231220060477N1
Enrollment
12
Registered
2024-06-13
Start date
2024-06-09
Completion date
Unknown
Last updated
2024-06-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Headache. Other headache syndromes

Interventions

Intervention 1: Intervention group: Ketorolac prescription 30 mgr intravenous with 30 mgr/2mL ampoules by 5 cc syringes. Intervention 2: Intervention group2: Haloperidol receivers 1 mgr intravenous wi

Sponsors

Tehran University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 55 Years

Inclusion criteria

Inclusion criteria: patients aged 18 to 55 who have visited the emergency room with the main complaint of headache.

Exclusion criteria

Exclusion criteria: Abnormal blood pressure(>200/100 mmhg) thunderclap (normal to the worst pain due to short time) fever acute trauma history of brain mass history of stroke history of anatomic malformation of brain Qtc>450 ms in EKG altered mental status (GCS<15) Haloperidol allergy Ketorolac allergy airway disease such as asthema active peptic ulcer advanced renal failure recent major sergury new FND any suspicious which lead to use of CT scan or LP pregnancy QT interval prolong drugs hepatic failure epilepsy or history of seizure hyperthyroidism parkinsonism chronic psychiatrics disease Concomitant use or within 2 weeks of discontinuing an MAOI inhibitor active gastritis history of GI bleeding Previous participation in the same study Previous enrollment in a study that may interfere with the current study Lack of consent to participate in the study Unwillingness to sign the consent form

Design outcomes

Primary

MeasureTime frame
Pain reduction. Timepoint: 15 , 30 , 60 mintes. Method of measurement: Visual analogue scale.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactAlireza Jalali

Tehran University of Medical Sciences

a.jalalll85@gmail.com+98 21 6312 1432

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026