Stroke, aphasia, brain stimulation. Aphasia
Conditions
Interventions
Intervention 1: Intervention group: The active stimulation group will apply transcranial stimulation of the left hemisphere with an intensity of 1.5 mA and for 20 minutes for 7 consecutive days. The
Sponsors
Kerman University of Medical Sciences
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: Inclusion criteria include Cortical aphasia caused by acute ischemic stroke (5 days after stroke) Age 18-80 years Persian mother Language Being right-handed Having the ability to speak before the stroke Having the ability to participate during treatment
Exclusion criteria
Exclusion criteria: Exclusion criteria included having brain damage before stroke having aphasia before stroke hemorrhagic stroke having subcortical aphasia contraindications to brain stimulation including metallic brain implant, pacemaker use of sodium and calcium channel blockers use psychoactive drugs or Effects on the CNS alcohol and drug abuse mental illness or neurological conditions other than stroke including epilepsy, cerebral palsy and dementia severe TDCS-related complications and patient dissatisfaction
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Language function score. Timepoint: Before treatment, immediately after treatment, one week after treatment, two weeks after treatment, one month after treatment, three months after treatment. Method of measurement: P-WAB-1 test.;Communication performance score. Timepoint: Before treatment, immediately after treatment, one week after treatment, two weeks after treatment, one month after treatment, three months after treatment. Method of measurement: communication activity log(CAL).;Quality of life score. Timepoint: Before treatment, immediately after treatment, one week after treatment, two weeks after treatment, one month after treatment, three months after treatment. Method of measurement: Stroke and Aphasia Quality of Life Scale-39(SAQOL-39).;MicroRNA experssion. Timepoint: Before treatment, immediately after treatment, one week after treatment. Method of measurement: Real-time polymerase chain reaction(PCR) kit. | — |
Secondary
| Measure | Time frame |
|---|---|
| MicroRNA expression. Timepoint: Before treatment, immediately after treatment, one week after treatment. Method of measurement: Real-time PCR method. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactAsghar Haghjoo
Kerman University of Medical Sciences
Outcome results
None listed