Femoral bone fracture. Fracture of femur
Conditions
Interventions
Intervention 1: Intervention group: Intravenous infusion of lidocaine (3 mg/kg during 20 minutes, Maximum dose 200 mg). Intervention 2: Control group: Intravenous pethidine (25 mg).
Sponsors
Artesh University of Medical Sciences
Eligibility
Sex/Gender
All
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: Age >= 18 years-old Femoral bone fracture Severe pain based on numerical rating scale of pain (NRS) (NRS>=7)
Exclusion criteria
Exclusion criteria: Age > 70 years-old Crush injury of limb and open fractures Acute diseases except of fractures Pregnancy Presence or history of cardiac block or bradycardia Presence or history of seizure Neuromuscular diseases Neuropathic disease Diabetes History of consumption of analgesic or anti-inflammatory drugs History of opioids consumption Allergic history of lidocaine and pethidine
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Numerical Rating Scale of Pain. Timepoint: Before drug administration, 10, 20, 30, 40, 50, 60 minutes after drug administration. Method of measurement: Visual Analogue Scale (VAS) for Pain. | — |
Secondary
| Measure | Time frame |
|---|---|
| Drug adverse events. Timepoint: During the 4 hours after drug administration. Method of measurement: Vital sign monitoring and evaluating the signs and symptoms. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactMehrshad Namazi
Artesh University of Medical Sciences
Outcome results
None listed