medial compartment osteoarthritis of the knee. Osteoarthritis of knee
Conditions
Interventions
Intervention 1: Intervention group: The intervention group includes patients who undergo only a fibula osteotomy, without any osteotomy in the tibia.In this method, first, a longitudinal incision of a
Sponsors
Tehran University of Medical Sciences
Eligibility
Sex/Gender
All
Age
40 Years to No maximum
Inclusion criteria
Inclusion criteria: Age = 40 years Kellgren–Lawrence grade II or III isolated medial tibiofemoral OA on weight-bearing radiographs Varus alignment = 7° Knee flexion = 90°
Exclusion criteria
Exclusion criteria: Prior knee surgery or fracture Inflammatory or post-traumatic arthritis Radiographic lateral or patellofemoral OA Medial proximal tibial angle (MPTA) 35 kg/m²
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Change in the pain subscale score on the Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) from baseline to 12 months after surgery. This score is a numerical score between 0 and 20 and indicates the severity of patients' pain in daily activities. This variable was selected as the main outcome of the study because it reflects the degree of improvement in patients' pain symptoms, which is the main goal of the surgical intervention. Timepoint: Measurement of the pain score on the Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) at baseline (before surgical intervention) and 12 months after the intervention. Method of measurement: Pain severity will be measured using a validated Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) questionnaire in Persian and self-reported by the patient. The pain score of this questionnaire is a number between zero (no pain) and twenty (very severe pain intensity) and is calculated using the total score of the pain-related questions. | — |
Secondary
| Measure | Time frame |
|---|---|
| Change in physical performance score in the Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) questionnaire from the beginning of the study to twelve months after the intervention. This numerical variable is between zero and sixty-eight and indicates the degree of functional disability of patients in performing daily activities. This variable is considered as a secondary outcome to evaluate the effect of surgical intervention on the functional ability of patients. Timepoint: Measurement of physical performance score in the WOMAC questionnaire at the beginning of the study (before surgical intervention), one month, six months and twelve months after the intervention. Method of measurement: Measurement of physical performance of patients will be carried out through a valid Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) questionnaire in Persian and in a self-reported manner by the patient. The performance score in this questionnaire is a number between zero (no functional problems) and sixty-eight (the highest level of disability).;Change in active knee range of motion (including knee flexion and extension) in degrees, which is considered an objective indicator of improvement in joint function after surgical intervention. This variable is especially important in assessing the impact of surgery on joint flexibility and return to daily activities. Timepoint: Knee range of motion measurement at the beginning of the study (before surgical intervention), one month, six months, and twelve months after the intervention. Method of measurement: Knee flexion and extension angles are measured by a trained physiotherapist using a goniometer. This tool records joint angles with high accuracy and the results are reported numerically in degrees.;The patients' functional and clinical score based on the Knee Society Score, which includes two separate sections to assess the clinical condition of the knee (including pain, range of motion, stab | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactMohammad Ayati Firouzabadi
Tehran University of Medical Sciences
Outcome results
None listed