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The Effect of Mucosal Micro-needling for Nystatin Delivery in the Treatment of Denture Stomatitis

The Effect of Mucosal Micro-needling for Nystatin Delivery in the Treatment of Denture Stomatitis- A Randomized Clinical Trial

Status
Recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20231209060307N2
Enrollment
10
Registered
2024-12-12
Start date
2024-11-30
Completion date
Unknown
Last updated
2025-01-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Denture stomatitis. Candidal stomatitis

Interventions

Intervention 1: Intervention group: Part of the lesion in the palate where microneedle is applied and nystatin mouthwash is given .The patient is taught to place and hold the microneedle on a randomly

Sponsors

Semnan University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
25 Years to No maximum

Inclusion criteria

Inclusion criteria: Have informed consent to participate in the study. They use complete and partial upper jaw dentures. People who have bilateral involvement of the lesion with a width of at least 2 cm.

Exclusion criteria

Exclusion criteria: Addiction to cigarettes and drugs History of allergy to antifungals such as nystatin Pregnant or lactating people Volunteers who have adverse drug reactions (such as an allergic reaction to any drug) Patients with uncontrolled systemic diseases

Design outcomes

Primary

MeasureTime frame
Healing the lesion caused by the denture. Timepoint: At the beginning of the study and after 5 and 10 days. Method of measurement: By visual inspection (0- Absence of denture stomatitis 1-mild redness 2-moderate to severe redness 3-granular surface).

Countries

Iran (Islamic Republic of)

Contacts

Public ContactNahid Karbasi

Semnan University of Medical Sciences

Sov.karbasi@gmail.com+98 23 3522 6200

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026