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curcumin effect in tooth extraction healing

Investigating the effectiveness of the topical use of curcumin on the wound healing process after molar teeth extraction

Status
Recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20231205060267N1
Enrollment
34
Registered
2023-12-06
Start date
2023-12-22
Completion date
Unknown
Last updated
2024-01-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Wound healing status after molar tooth extraction. Open wound of lip and oral cavity

Interventions

Intervention 1: Intervention group: 500 mg of curcumin capsule mixed with 2 ml of normal saline is placed on a gel tampon and then placed on the wound. Intervention 2: Control group: Only 2 ml of norm

Sponsors

Islamic Azad University
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: Candidates for extraction of unmaintainable molar teeth

Exclusion criteria

Exclusion criteria: Patients with vascular or blood disorders Users of exogenous corticosteroids and anticoagulants such as aspirin Patients with a history of asthma and allergies Patients with uncontrolled systemic disorders, patients with uncontrolled respiratory, digestive, renal and pulmonary cardiovascular diseases Patients with a history of head and neck radiotherapy or chemotherapy Patients with dry mouth Patients with a history of developing a dry socket after tooth extraction Consumers of removable prostheses pregnant women and nursing mothers Patients with systemic fungal infections, acute infections and tuberculosis (active or silent) Patients who have used painkillers or anti-inflammatories in the week leading up to tooth extraction Patients who consume any amount of cigarettes, alcohol, drugs or stimulants The tooth in question has been symptomatic in the week leading up to the extraction

Design outcomes

Primary

MeasureTime frame
Wound healing score in clinical examination. Timepoint: Wound healing scoring on day 7 and 14 after tooth extraction. Method of measurement: Scoring of wound healing is based on four criteria: tissue color, response to palpation, the presence of granulation tissue, and the state of the wound margin during clinical examination.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactMostafa Sharifzadeh

Islamic Azad University

mostafa.a.sharifzadeh@gmail.com+98 21 7795 3395

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026