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Medical versus surgical treatment for chronic anal fissure

Comparison between treatment efficacy of glyceryl trinitrate and lateral sphincterotomy for chronic anal fissure

Status
Active, not recruiting
Phases
Phase 2
Study type
Interventional
Source
IRCT
Registry ID
IRCT20231201060234N1
Enrollment
240
Registered
2024-06-22
Start date
2023-01-01
Completion date
Unknown
Last updated
2024-06-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Chronic anal fissure. Chronic anal fissure

Interventions

Intervention 1: Intervention group 1: Surgical lateral sphincterotomy group. Patients in Group S received the surgical procedure by a consultant surgeon and part of the internal anal sphincter was dis

Sponsors

CMH Peshawar
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: Patients more than 18 years of age With a chronic non-healing anal fissure more than 8 weeks duration Presenting to the surgical out-patient department for treatment.

Exclusion criteria

Exclusion criteria: Pregnancy Recurrent anal fissures Major cardiac or respiratory disease Unwilling to be included in the study

Design outcomes

Primary

MeasureTime frame
Mean time to complete fissure healing. Timepoint: Assessed weekly after intervention till endpoint of healing or failure of healing after 8 weeks. Method of measurement: Subjective assessment by a surgical consultant.

Secondary

MeasureTime frame
Median pain scores. Timepoint: Weekly will 8 weeks. Method of measurement: Visual analog pain score by a surgical consultant.;Episodes of bleeding post-procedure. Timepoint: Weekly for 8 weeks after procedure. Method of measurement: Assessment subjectively by.a consultant surgical specialist.

Countries

Pakistan

Contacts

Public ContactRashid Ali

CMH Peshawar

Rashid_zahidbaloch@hotmail.com+92 81 2850639

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026