Acne Vulgaris. Acne vulgaris
Conditions
Interventions
Intervention 1: Control group: Benzoyl Peroxide Gel 5% twice a day topically plus Doxycycline 100 mg capsule twice a day orally Plus Cephalic vein phelebotomy in the elbow crease area with an 18 Gauge
Sponsors
Mashhad University of Medical Sciences
Eligibility
Sex/Gender
All
Age
16 Years to 25 Years
Inclusion criteria
Inclusion criteria: People aged 16 to 25 years Moderate to severe acne based on GAGS criteria Not having general cold Mizaj (temperament) based on diagnosis of traditional Persian medicine expert and valid Mizaj questionnaire Willingness to cooperate in the project
Exclusion criteria
Exclusion criteria: Having other skin diseases other than acne Having serious liver and kidney diseases Patients with iron deficiency anemia Use of topical acne medicine in the last 2 weeks or any systemic anti-acne antibiotic treatment in the last 1 month or isotretinoin in the last 6 months Use of acne-causing drugs in the last month Chemical or laser peeling or UV treatment or photosensitizing drugs in the last month Drug sensitivity to tetracycline derivatives or benzoyl peroxide General cold temperament based on validated Mezaj questionnaire Body Mass Index lower than 19 Breastfeeding Pregnancy Patients diagnosed with Polycystic ovary syndrome Mentally retarded patients
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Acne severity according to Global Acne Grading Score Index. Timepoint: At beginning of study and end of every month till 3 month. Method of measurement: Global Acne Grading Score Index. | — |
Secondary
| Measure | Time frame |
|---|---|
| Quality of Life according Cardiff Disability Index. Timepoint: At beggining of Study and end of 3th month. Method of measurement: According Cardiff Acne Disability Index. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactMostafa Khosravi Moghaddam
Mashhad University of Medical Sciences
Outcome results
None listed