Skip to content

Evaluation of the effect of Zataria multiflora extract mouthwash on prevention of chemotherapy induced oral mucositis

Evaluation of the effectiveness of Zataria multiflora extract mouthwash on prevention of chemotherapy induced oral mucositis In patients undergoing chemotherapy

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20231126060189N1
Enrollment
78
Registered
2024-01-23
Start date
2024-02-19
Completion date
Unknown
Last updated
2024-03-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

chemotherapy induced oral mucositis. Oral mucositis (ulcerative) due to antineoplastic therapy

Interventions

Intervention 1: Intervention group: For 21 days, three times a day and half an hour before chemotherapy, they gargle 5 ml of Protect containing Zataria Multiflora(Zulang Respina Pharmaceutical Company

Sponsors

Birjand University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
20 Years to 70 Years

Inclusion criteria

Inclusion criteria: Chemotherapy is indicated Age should be between 20 and 70 years Be alert and able to use mouthwash The chemotherapy regimen should contain 5-fluorouracil

Exclusion criteria

Exclusion criteria: The presence of traumatizing teeth or traumatizing dentures Receiving radiotherapy in addition to chemotherapy Pregnancy or breastfeeding

Design outcomes

Primary

MeasureTime frame
Mucositis grade. Timepoint: Days 0, 7, 14 and 21 after starting cancer treatment. Method of measurement: Clinical examination by a dentist based on World Health Organization oral mucositis grading scale.

Secondary

MeasureTime frame
Pain index. Timepoint: Days 0, 7, 14 and 21 after starting cancer treatment. Method of measurement: Visual Analogue Scale and McGill Pain Questionnaire.;Mucositis incidence time. Timepoint: Days 0, 7, 14 and 21 after starting cancer treatment. Method of measurement: Weekly clinical examination by a dentist.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactMohamad Amir Mohamadifard

Birjand University of Medical Sciences

mohamadamir_mohamadifard@yahoo.com+98 56 3162 6800

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026