Diabetic retinopathy is one of the most important causes of blindness in the world, and due to the fact that it affects people of working age, it has tremendous socio-economic consequences in societies. (1) The prevalence of DME in diabetic patients in Iran is estimated to be around 30%. (DME, Diabetic Macular Edema) can be defined as macular thickening and cystoid edema, which can cause diabetic retinopathy mostly with exudate deposition.. Diabetes mellitus due to underlying condition with mil
Conditions
Interventions
Intervention 1: Intervention group 1: the eye receiving xylomol drops. One day before the intravitreal injection of bevacizumab, drops are placed every 8 hours in the eye that will be injected, and af
Sponsors
Zahedan University of Medical Sciences
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: People with bilateral diabetic macular edema (central retinal thickness more than 300 microns) with center-involved and thickness difference less than 25% between 2 eyes who have not undergone any eye interventions (such as eye surgery, intraocular injection) eye, eye lasers and eye treatment and eye local treatment) are not included.
Exclusion criteria
Exclusion criteria: Patients during pregnancy and breastfeeding Active intraocular inflammation treated with topical corticosteroids Eye pathologies such as pterygium or corneal opacities that can affect the evaluation of study variables A patient with high eye pressure who is treated with intraocular pressure lowering drugs and corticosteroids History of allergy to CAIs and sulfonamide drugs Patients who use systemic antihypertensive drugs such as acetazolamide or beta blockers
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Central thickness of macula. Timepoint: Before intervention-1month -2month-3month post IVB and drop. Method of measurement: - measurement using macular OCT imaging.;IOP. Timepoint: Before intervention-1month -2month-3month post IVB and drop. Method of measurement: measurement by Goldman tonometer. | — |
Secondary
| Measure | Time frame |
|---|---|
| Visual acuity. Timepoint: Before intervention and one ,two,three month post. Method of measurement: LogMar. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactMaryam Dianat
Zahedan University of Medical Sciences
Outcome results
None listed