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Evaluation of the effect of non-surgical periodontal treatment on biochemical indicators of metabolic syndrome

Evaluation of the effect of non-surgical periodontal treatment on biochemical indicators of metabolic syndrome: A Controlled Randomized Clinical Trial

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
IRCT
Registry ID
IRCT20231123060153N3
Enrollment
54
Registered
2025-05-20
Start date
2025-04-29
Completion date
Unknown
Last updated
2025-07-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Condition 1: Metabolic syndrome. Condition 2: Non-surgical periodontal treatment. Condition 3: Chronic periodontitis. Metabolic syndrome Chronic periodontitis

Interventions

Intervention 1: Intervention group:The intervention group treatment is built on oral health education and non-surgical periodontal therapy.The oral health educations content consists brushing techniqu

Sponsors

Gorgan University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
35 Years to 60 Years

Inclusion criteria

Inclusion criteria: Patients with 1st or 2nd Stage of periodontitis Ages between 35 to 60 Definitive metabolic syndrome diagnosis in both groups Having at least 20 teeth Consent for participation

Exclusion criteria

Exclusion criteria: Having any kind of disease that could effect periodontal tissue other than matabolic syndrome like: Papillon-lefevre? Treacher Collins? Aggressive periodontitis? AIDS and End Stage Renal Disease Taking any medication that could effect periodontal tissue such as: Nifedipine and Phenytoin Using orthodontic treatments or fixed long span prostheses or removable prostheses Taking Anti-biotics? Immunosuppressive drugs or Non-steroidal anti-inflammatory drugs for one week in last six month Using periodontal treatment in last six month

Design outcomes

Primary

MeasureTime frame
Fasting blood sugar factor value in blood test. Timepoint: Measuring the level of fasting blood sugar before the intervention and 3 and 6 months after the end of intervention. Method of measurement: Glucometer.;Triglycerides factor value in blood test. Timepoint: Measuring the level of triglyceride before the intervention and 3 and 6 months after the end of intervention. Method of measurement: Triglyceride Oxidase method.;Cholesterol factor value in blood test. Timepoint: Measuring the level of cholesterol before the intervention and 3 and 6 months after the end of intervention. Method of measurement: Cholesterol Oxidase method.;HDL factor value in blood test. Timepoint: Measuring the level of HDL before the intervention and 3 and 6 months after the end of intervention. Method of measurement: Enzymatic method.;Abdominal obesity in centimeters. Timepoint: Measuring the level of abdominal obesity before the intervention and 3 and 6 months after the end of intervention. Method of measurement: Tape measure.;Blood pressure. Timepoint: Measuring Blood pressure before the intervention and 3 and 6 months after the end of intervention. Method of measurement: Mercury sphygmomanometer.

Secondary

MeasureTime frame
Gingival recession. Timepoint: Measuring the amount of gingival recession before the intervention and 3 and 6 months after the end of the intervention. Method of measurement: Williams periodontal probe.;Clinical Attachment Loss. Timepoint: Measurement of clinical attachment loss before intervention and 3 and 6 months after the end of intervention. Method of measurement: Williams periodontal probe.;Pocket probing depth. Timepoint: Measurement of pocket probe depth before intervention and 3 and 6 months after the end of intervention. Method of measurement: Williams periodontal probe.;Plaque index. Timepoint: Measurement of plaque index before intervention and 3 and 6 months after the end of intervention. Method of measurement: Silness & Loe index.;Bleeding on probing. Timepoint: Measurement of bleeding on probing before the intervention and 3 and 6 months after the end of the intervention. Method of measurement: Williams periodontal probe.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactAmir reza Ahmadinia

Gorgan University of Medical Sciences

ar.ahmadinia@gmail.com+98 17 3253 6270

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026