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Comparison of the effect of chlorhexidine and Persica mouthwash in the prevention of ventilator associated pneumonia in patients under ventilator

Comparison of the effect of chlorhexidine and Persica mouthwash in the prevention of ventilator associated pneumonia in patients under ventilator admitted to the intensive care unit

Status
Recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20231122060135N1
Enrollment
60
Registered
2024-01-22
Start date
2024-01-21
Completion date
Unknown
Last updated
2024-03-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

ventilator associated pneumonia. Ventilator associated pneumonia

Interventions

Intervention 1: Intervention group: Patients in this group will receive15 ml of pre-prepared solution containing 0.2% chlorhexidine (Iran Najo Pharmaceutical Company) alone 2 times a day for 5 days. T

Sponsors

Zabol University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 65 Years

Inclusion criteria

Inclusion criteria: No damage to the mouth, jaw and face Oral health assessment checklist score 10 and less Clinical score of lung infection less than 6 on arrival The patient should be Undergo airway intubation on the first day The patient should remain intubated for at least 72 hours No immunosuppression due to certain drugs or diseases

Exclusion criteria

Exclusion criteria: Malignancy Diabetes Chronic obstructive pulmonary disease History of broad-spectrum antibiotic therapy in the last 3 months Dissatisfaction of patient or his/her companion to participate in the study

Design outcomes

Primary

MeasureTime frame
Ventilator associated pneumonia. Timepoint: Ventilator associated pneumonia will be determined 5 days after the intervention. Method of measurement: Clinical Pulmonary Infection Score.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactMostafa Mirzaei

Zabol University of Medical Sciences

MOSTAFA.M.F9191@GMAIL.COM+98 54 3222 5402

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026