Investigating the effect of balance salt solution temperature zero degrees on pain control after photorefractive keratectomy

effect of balanced salt solution temperatures in pain control and corneal epithelium healing after photorefractive keratectomy

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20231114060059N1

Enrollment

116

Registered

2025-11-18

Start date

2024-08-22

Completion date

Unknown

Last updated

2025-12-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Refractive error.

Interventions

In this study, in one patients eye, room temperature balanced salt solution is poured during and after photorefractive keratectomy (control group) and in the other eye, zero degree balanced salt solu

Eligibility

Sex/Gender

All

Age

20 Years to 40 Years

Inclusion criteria

Inclusion criteria: pation with myopia and myopic astigmatism the degree of myopia is 1 to 5 diopters the amount of astigmatism is 0 to 4 diopters

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Pain level after photorefractive keratectomy. Timepoint: Within 5 days after photorefractive keratectomy. Method of measurement: Pain level after photorefractive keratectomy based on visual analogue scale in 6 hours after photorefractive keratectomy and on days 1, 3 and 5 after photorefractive keratectomy.;Corneal epithelium repair rate after photorefractive keratectomy. Timepoint: Within 5 days after photorefractive keratectomy. Method of measurement: The amount of epithelium repair based on the remaining defect area with Slate Photo on days 1, 3 and 5 after photorefractive keratectomy.	—

Measure

Time frame

Pain level after photorefractive keratectomy. Timepoint: Within 5 days after photorefractive keratectomy. Method of measurement: Pain level after photorefractive keratectomy based on visual analogue scale in 6 hours after photorefractive keratectomy and on days 1, 3 and 5 after photorefractive keratectomy.;Corneal epithelium repair rate after photorefractive keratectomy. Timepoint: Within 5 days after photorefractive keratectomy. Method of measurement: The amount of epithelium repair based on the remaining defect area with Slate Photo on days 1, 3 and 5 after photorefractive keratectomy.

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Countries

Iran (Islamic Republic of)

Contacts

Public Contactmohamadreza sedaghat

Mashhad University of Medical Sciences

sedaghatMR@mums.ac.ir+98 51 3728 1401

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026