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The comparison of cardiac rehabilitation protocols (functional and ordinary) on atherosclerosis biomarkers and functional capacity in coronary arteries patients

The comparison of the effect of two cardiac rehabilitation protocols (functional and ordinary) on atherosclerosis biomarkers and functional capacity in coronary arteries patients

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
IRCT
Registry ID
IRCT20231111060023N1
Enrollment
30
Registered
2023-11-30
Start date
2023-10-23
Completion date
Unknown
Last updated
2024-01-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Coronary artery disease. Atherosclerotic heart disease of native coronary artery

Interventions

Intervention 1: Functional group: Functional training group: In the functional training group, moderate functional training (MIFT) will be used, which will include performing functional movements in a

Sponsors

Allameh Tabataba'i University
Lead Sponsor

Eligibility

Sex/Gender
Male
Age
50 Years to No maximum

Inclusion criteria

Inclusion criteria: Coronary artery patients who have surgery, usage of Beta blockers, patients who are over 50 years old, have hypertension, smoking, dyslipidemia, do not have a history of regular exercise, and participate in cardiac rehabilitation programs.

Exclusion criteria

Exclusion criteria: Usage of Alcohol. Disabled to do exercise, having a history of regular exercise training.

Design outcomes

Primary

MeasureTime frame
Apo-B. Timepoint: 24 hours before the intervention and 72 hours after the intervention. Method of measurement: In order to measure the amount of apoB, 10 cc of blood is taken first. Then 3-4 cc of it will be frozen and then placed in a centrifuge. The samples will be kept at a temperature of 20 degrees and then frozen at a temperature of 70 degrees Celsius. Finally, they will be measured using the biomarker kit from the isolated plasma.;MPO. Timepoint: 24 hours before the intervention and 72 hours after the intervention. Method of measurement: In order to measure the amount of MPO, 10 cc of blood is taken first. Then 3-4 cc of it will be frozen and then placed in a centrifuge. The samples will be kept at a temperature of 20 degrees and then frozen at a temperature of 70 degrees Celsius. Finally, they will be measured using the biomarker kit from the isolated plasma.

Secondary

MeasureTime frame
6MWT. Timepoint: 24 hours before the intervention and 72 hours after the intervention. Method of measurement: It is a simple and inexpensive test, well tolerated by the patient. Also, a walking test for 6 minutes is an alternative to a cardiopulmonary exercise test (CPET) for risk classification in heart failure patients. The walking test should be performed for 6 minutes, preferably inside a closed space, on a flat surface in a corridor with a hard surface, and on a straight path that is usually at least 30 meters long. The patient is told to keep calm, take his medication, and wear comfortable clothes and shoes. The observer records baseline oxygen saturation, heart rate, brachial arterial blood pressure, and Borg scale ratings for dyspnea and fatigue. Now the patient understands the relevant instructions and then prepares to start the test. The walking path must be marked every 3 meters. It is also recommended to place cones at the turns of the paths. During the test, the participants are required to walk at a suitable speed according to their conditions, and they are allowed to do so if they wish to do so. Slow down in the road and stop. Then continue walking as soon as possible. The supervisor should always be ready to provide encouragement to the patient with appropriate phrases such as "You are doing well" and "Keep doing what you are doing". Encouragement has been shown to affect distance traveled, especially in the pediatric population. At the end of the test, the observer again records the Borg scale for shortness of breath and fatigue, and then selectively measures arterial blood pressure, heart rate, and oxygen saturation. The number of laps and additional distance covered by the registration and test is calculated by 6 minutes of walking.;TUG. Timepoint: 24 hours before the intervention and 72 hours after the intervention. Method of measurement: The test of getting up and walking is the ability to perform consecutive movement tasks compared to walking a

Countries

Iran (Islamic Republic of)

Contacts

Public ContactRasoul Eslami

Allameh Tabataba'i University

eslami.rasul@gmail.com+98 21 4839 0000

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026