Investigating the effect of topical ketoconazole in preventing fungal peritonitis in children undergoing peritoneal dialysis

Status

Recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20231111060021N1

Enrollment

Registered

2023-11-26

Start date

2023-09-23

Completion date

Unknown

Last updated

2024-01-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Child– Ketoconazole – Fungal Peritonitis – Chronic Peritoneal Dialysis..

Interventions

Control group: Control group(s) (placebo, no placebo):The control group is the same group that did not receive prophylaxis in the last year.

Eligibility

Sex/Gender

All

Age

6 Years to 18 Years

Inclusion criteria

Inclusion criteria: Children undergoing peritoneal dialysis Absence of underlying skin diseases based on initial clinical evaluation Not have fungal peritonitis Informed consent Age 6 to 18 years

Exclusion criteria

Exclusion criteria: Diffuse infection requires receiving broad_spectrum antibiotics Having an open wound at the exit site of the catheter Need to change the catheter Incidence of skin sensitivity with topical ketoconazole

Design outcomes

Primary

Measure	Time frame
Evaluating the effectiveness of topical use of 2% ketoconazole shampoo in preventing fungal peritonitis in children with peritoneal dialysis. Timepoint: Smear and culture of peritoneal fluid for fungi and bacteria are taken from patients before shampooing and after three months and after six months. Method of measurement: Returned peritoneal fluid culture and smear.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactSara Saadat

Mashhad University of Medical Sciences

SaadatS@mums.ac.ir+98 51 3726 9021

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026