Hypercholesterolemia. Dietary counseling and surveillance
Conditions
Interventions
Intervention 1: Intervention group: Capsules containing Lactobacillus Rotari in the amount of 5x10^8 CFU- once a day. Intervention 2: Control group: Capsules containing starch.
Sponsors
Mashhad University of Medical Sciences
Eligibility
Sex/Gender
All
Age
20 Years to 70 Years
Inclusion criteria
Inclusion criteria: THE AGE OF OUR participant will be between 20 to 70 years old; their total cholesterol plasma level will be above 200 mg/dl; HDL-C plasma level under 70 mg/dl; BMI will be between 20 to 45 kg/m2; they should sign informed consent
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The percentage of patients calculated by SCORE in each group had LDL with a suitable range for lifestyle modification, in the patients of Cardiovascular Clinic of Qaem Hospital. Timepoint: The lipid profile of the patients is measured before the start of the study, 30 days and then 60 days after taking the drugs. Method of measurement: Initial lipid profile testing. | — |
Secondary
| Measure | Time frame |
|---|---|
| Secondary effects:1-Percentage of acute coronary syndrome (ACS: Unstable angina, NSTEMI, STEMI)2- Percentage of incidence of metabolic syndrome (by examining each metabolic syndrome criteria: abdominal circumference, fasting blood sugar level, HDL level, TG level, blood pressure level) in future monthly visits3. The percentage of LDL serum levels of patients after the study. Timepoint: Before starting the study, 30 days later and then 60 days after taking the capsules. Method of measurement: Description of oral condition in the form of an interview for the occurrence of ACS - use of sphygmomanometer to measure blood pressure - use of routine lipid profile tests and fasting blood sugar. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactBahman Khameneh Bagheri
Mashhad University of Medical Sciences
Outcome results
None listed