Healthy volunteer.
Conditions
Interventions
Intervention 1: Intervention group 1 receives an Iranian drug and blood concentrations are obtained at specific time intervals. In the second series, this group receives the brand name drug. Intervent
Sponsors
Arang Daroo Darman
Eligibility
Sex/Gender
Male
Age
18 Years to 60 Years
Inclusion criteria
Inclusion criteria: Must be in good general health (liver, heart, and kidneys). Body mass index should be in the range of 18-28. Informed consent must be obtained. Age must be between 18-60 years.
Exclusion criteria
Exclusion criteria: History of allergic or adverse reaction to eltrombopag or any similar product. Addiction to cigarettes, alcohol, or any type of drug Volunteers with a history of chronic diseases such as high blood pressure or high blood lipids, etc. who have taken medication in the past two months.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| At specific intervals, the blood concentration of the drug is measured and compared in two series of blood draws, and it is determined whether the drugs are equivalent or not. Timepoint: Drug concentrations are measured at time intervals of 0, 0.5, 1, 1.5, 2, 2.5, 3, 4, 6, 8, 10, 12, 24, 48, and 72 hours after drug administration. Method of measurement: Liquid chromatography with dual mass spectrometer LC/MS/MS. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactSaeed Ghanbarzadeh
Phayesh Daroo Zist Azma
Outcome results
None listed