Comparative bioequivalence Study of the Mefenamic acid 250 mg capsule, Manufactured by Slhavi Pharmaceutical Company

Comparative Bioequivalence Study of the Mefenamic acid 250 mg Capsule, Manufactured by ?Alhavi Pharmaceutical Company by Innovative Company

Status

Active, not recruiting

Phases

Phase 1

Study type

Interventional

Source

IRCT

Registry ID

IRCT20231108059993N15

Enrollment

Registered

2026-02-14

Start date

2026-02-20

Completion date

Unknown

Last updated

2026-06-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Healthy volunteers were enrolled in the study..

Interventions

Intervention 1: Intervention group: In this study, 24 volunteers were divided into two groups. The first group took Iranian medicine and the second group took brand medicine. After a one-week period,

Eligibility

Sex/Gender

Male

Age

18 Years to 55 Years

Inclusion criteria

Inclusion criteria: Good general health (liver, heart, and kidneys). Body mass index (18-28). Informed consent Ages range (18-55 years).

Exclusion criteria

Exclusion criteria: Addiction to alcohol, Allergy to Mefenamic C Allergy to Mefenamic ?Acid Chronic disease treatment history

Design outcomes

Primary

Measure	Time frame
The volunteers are divided into two groups, and the first group takes the Iranian-made drug mefenamic acid. Timepoint: 0 , 0/5 , 1 , 1/5, 2 , 2/5 , 3 , 4, 5 , 6 , 8 , 10 ? 24????. Method of measurement: Liquid chromatography with dual mass spectrometer (LC/M?S/MS).;The second group of 12 will take the brand name mefenamic acid (Ponstan). Timepoint: 0 , 0/5 , 1 , 1/5, 2 , 2/5 , 3 , 4, 5 , 6 , 8 , 10 ? ????. Method of measurement: Liquid chromatography with dual mass spectrometer (LC/M?S/MS).	—

Measure

Time frame

The volunteers are divided into two groups, and the first group takes the Iranian-made drug mefenamic acid. Timepoint: 0 , 0/5 , 1 , 1/5, 2 , 2/5 , 3 , 4, 5 , 6 , 8 , 10 ? 24????. Method of measurement: Liquid chromatography with dual mass spectrometer (LC/M?S/MS).;The second group of 12 will take the brand name mefenamic acid (Ponstan). Timepoint: 0 , 0/5 , 1 , 1/5, 2 , 2/5 , 3 , 4, 5 , 6 , 8 , 10 ? ????. Method of measurement: Liquid chromatography with dual mass spectrometer (LC/M?S/MS).

—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactSaeed Ghanbarzadeh

Tabriz University of Medical Sciences

s_ghanbarzadeh@yahoo.com+98 41 3467 9114

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Jun 11, 2026