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The effect of hydrotherapy and Tdcs stimulation on knee arthritis

Comparing the Effectiveness of Six Weeks of Water Based Neuromuscular and transcranial direct current stimulation Exercises on Pain, Function, Knee Instability, and Quality of Life of Women with Knee Osteoarthritis and Knee Instability Characteristics.

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20231106059975N1
Enrollment
35
Registered
2024-07-08
Start date
2024-04-05
Completion date
Unknown
Last updated
2025-07-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Knee Osteoarthritis. Chapter XIIIDiseases of the musculoskeletal system and connective tissue(M00-M99)

Interventions

Intervention group: In this study, the participants were randomly selected based on the inclusion criteria with a ratio of 1 to 1 in the groups of neuromuscular exercises in water (n=20) and neuromusc

Sponsors

Razi University
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
40 Years to No maximum

Inclusion criteria

Inclusion criteria: Age more than 40 years- Having the clinical criteria of the American College of Rheumatology for knee OA (Altman et al., 1986) reported knee instability- Self-Estimating the scale of radiographic disease severity of Kellgren and Lawrence = II

Exclusion criteria

Exclusion criteria: Body mass index greater than or equal to BMI>40 kg/m2 Had a history of stroke, brain surgery, brain tumor, seizure, or intracranial metal implantation. Patients who are unable to walk without an assistive device. People who have neuromuscular disease (multiple sclerosis, Parkinson's, etc.). Patients who have undergone other interventions in the past three months. History of fractures and surgery in the lower extremities. Concomitant hip osteoarthritis, knee joint surgery, or being scheduled for arthroplasty. Hospitalization in the past year for mental illness. Uncontrolled blood pressure.

Design outcomes

Primary

MeasureTime frame
Pain intensity. Timepoint: Before starting training interventions and re-measurement after 6 weeks. Method of measurement: VAS visual pain intensity is used to measure the intensity of perceived pain. In this way, a 10 cm long horizontal ruler is placed in front of the patient, with zero at the beginning and 10 at the end, 0 (no pain) to 10 (the most severe pain). The obtained number will be recorded as the severity of the patient's knee pain.-.;Function. Timepoint: Before starting training interventions and re-measurement after 6 weeks. Method of measurement: Performance is one of the indicators of functional evaluation in patients with knee osteoarthritis using the WOMAC questionnaire, which contains five options, where the severe symptoms are graded from (0 none to 4 very severe) and the patient chooses one of them. "Womac" strength has three subscales of pain with a score of (0-20), stiffness with a score of joint stiffness (0-8), and physical performance with a score of (0-68). A higher score indicates more severe symptoms.;Knee instability. Timepoint: Before starting training interventions and re-measurement after 6 weeks. Method of measurement: Knee instability will be reported by the person himself using the Felson questionnaire. In response to the question, "Does the knee's degree of deviation, bending, or displacement affect your daily activities?" Rated as 5 = I have no symptoms; 4 = I have no symptoms but it does not affect my daily activities; 3 = Symptoms slightly affect my daily activities; 2 = Symptoms moderately affect my daily activities; 1 = severe symptoms affect my daily ADL activities; 0 = symptoms prevent me from doing all of my daily activities.;Muscles strength. Timepoint: Before starting training interventions and re-measurement after 6 weeks. Method of measurement: The strength of the knee (hip abductors and extensors; knee flexors and extensors groups muscles) will be evaluated using a manual Pull-Push dynamometer made in the United Stat

Secondary

MeasureTime frame
Plantar pressure distribution situation. Timepoint: Before starting training interventions and re-measurement after 6 weeks. Method of measurement: The condition of balance of subjects will be checked with a PT-Scan device (made in Iran).;Kinesiophobia. Timepoint: Before starting training interventions and re-measurement after 6 weeks. Method of measurement: TSK is a 17-item scale where each item is answered on a four-point Likert scale. Scores are given in a range of 4 (1 means completely disagree 4 means completely agree). The final score is 68-17. Scores above 37 indicate a high degree of phobia. Its 2, 1, and 4 factorial structural models have been implemented. Among them, the two-factor model is preferable and is used more due to its adaptation to the patient's conditions and different situations.;Gait kinematics and acceleration-movement. Timepoint: Before starting training interventions and re-measurement after 6 weeks. Method of measurement: Gait kinematics and acceleration-movement of the lower leg kinematic analysis of gait based on two-dimensional video D-GKA2 is a simple, practical, and inexpensive method in which two video cameras and passive markers are used. The patient is asked to walk on a treadmill at a speed of 1.5 m/s and video records are collected for 60 seconds; The recorded video records were analyzed using Kinovea software version 8.15, which is a free two-dimensional motion analysis software used to evaluate the kinematic parameters of walking. During the phases (midstance, pre-swing, midswing, late swing) that require a maximum range of motion in the knee and ankle joints, kinematic analyses will be performed in the sagittal plane and only in the knee and ankle joints. The filming process will last for six minutes; The first two minutes will not be recorded to familiarize yourself with the conditions of walking on the treadmill, and the last two minutes will not be recorded to avoid disturbing the usual walking condition, and only the midd

Countries

Iran (Islamic Republic of)

Contacts

Public ContactFarzaneh Gandomi

Razi University

gandomi777@gmail.com+98 83 3427 3272

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026