Post-Stroke Depression. Mood disorder due to known physiological condition with depressive features
Conditions
Interventions
Intervention group: 33 patients diagnosed with Post-Stroke Depression are given 5 mg of Escitalopram, and if there are no side effects, it is increased to 10 mg after two weeks, they are also given 10
Sponsors
University of social welfare and rehabilitation sciences
Eligibility
Sex/Gender
All
Age
20 Years to No maximum
Inclusion criteria
Inclusion criteria: Patients'age must be older than 20 years. ischemic stroke or intracerebral hemorrhage at least 21 days after cerebrovascular accident. Modified Rankin Scale (MRS) score must be 3 or less. Consent to participate in the study. Having a diagnosis of post-stroke depression with a HAM-D score above 8. The patients must be literate. MoCA must be above 18. Constant fatigue reported by the patient with an MFI-20 score equal to 12 or more.
Exclusion criteria
Exclusion criteria: History of depression, dementia or other psychiatric diseases before stroke Having other diagnoses with fatigue as a known symptom Use of Benzodiazepines or Antiepileptic drugs History of other brain diseases or trauma within 30 days before screening Pregnancy or intention to become pregnant, breastfeeding
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Depression score in Hamilton Depression Rating Scale. Timepoint: At the beginning of the study and 2, 4 and 6 weeks after the start of the intervention. Method of measurement: Depression score in Hamilton Depression Rating Scale.;Fatigue score in Fatigue Severity Scale. Timepoint: At the beginning of the study and 2, 4 and 6 weeks after the start of the intervention. Method of measurement: Fatigue Severity Scale.;Cognitive function score in Montreal Cognitive Assessment. Timepoint: At the beginning of the study and 2, 4 and 6 weeks after the start of the intervention. Method of measurement: Montreal Cognitive Assessment. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactNazila Jabbari Nejad
University of social welfare and rehabilitation sciences
Outcome results
None listed