evaluation of comparing the effectiveness of Unified Protocol and Dialectical Behavioral Therapy among individuals with borderline personality disorder and Post-traumatic stress disorder

comparing the effectiveness of Unified Protocol (UP) versus Dialectical Behavioral Therapy (DBT) in severity of borderline personality disorder and Post-traumatic stress disorder in individuals with both disorders

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

IRCT

Registry ID

IRCT20231106059970N2

Enrollment

Registered

2024-12-07

Start date

2024-11-21

Completion date

Unknown

Last updated

2025-01-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Condition 1: Borderline personality disorder. Condition 2: Post-traumatic Stress Disorder. Borderline personality disorder Post-traumatic stress disorder (PTSD)

Interventions

Intervention 1: Intervention group 1: The Unified Protocol (UP), is emotion-focused cognitive-behavioral therapy. It consists 5 core treatment modules: (1) mindful emotion awareness, (2) cognitive fle

Eligibility

Sex/Gender

All

Age

18 Years to 65 Years

Inclusion criteria

Inclusion criteria: Meet at least 5 out 9 Borderline personality disorder criteria of DSM-5-TR Meet Post-traumatic stress disorder criteria of DSM-5-TR at least 18 years old Be able to speak and read Farsi

Exclusion criteria

Exclusion criteria: intellectual disability change in dosage and type of psychiatric medicine 3-months prior to the study met criteria for a psychotic disorder, bipolar disorder, or organic mental disorder that assessed by SCID-5 (SCID-5) Required specialized treatment for high risk of suicide received 8 or more sessions of psychotherapies within last 5 years

Design outcomes

Primary

Measure	Time frame
Borderline personality symptoms severity. Timepoint: before intervention start, after intervention, 6,12,18,24, and 36 months after intervention as a follow-up phase. Method of measurement: using questionnaire Borderline symptoms checklist.;Post-traumatic stress symptoms severity. Timepoint: before intervention start, after intervention, 6,12,18,24, and 36 months after intervention as a follow-up phase. Method of measurement: by using Post-traumatic stress disorder checklist questionnaire.	—

Measure

Time frame

Borderline personality symptoms severity. Timepoint: before intervention start, after intervention, 6,12,18,24, and 36 months after intervention as a follow-up phase. Method of measurement: using questionnaire Borderline symptoms checklist.;Post-traumatic stress symptoms severity. Timepoint: before intervention start, after intervention, 6,12,18,24, and 36 months after intervention as a follow-up phase. Method of measurement: by using Post-traumatic stress disorder checklist questionnaire.

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Secondary

Measure	Time frame
Anger severity. Timepoint: before intervention start, after intervention, 6,12,18,24, and 36 months after intervention as a follow-up phase. Method of measurement: by using self-report the State–Trait Anger Expression Inventory–2 questionnaire.;Dissociative symptoms severity. Timepoint: before intervention start, after intervention, 6,12,18,24, and 36 months after intervention as a follow-up phase. Method of measurement: by using self-report the dissociative Experiences Scale questionnaire.;Emotion dysregulation severity. Timepoint: before intervention start, after intervention, 6,12,18,24, and 36 months after intervention as a follow-up phase. Method of measurement: by using the Difficulties in Emotion Regulation Scale questionnaire.;Self-harm severity. Timepoint: before intervention start, after intervention, 6,12,18,24, and 36 months after intervention as a follow-up phase. Method of measurement: by using self-report the deliberate Self-Harm Inventory questionnaire.;Emptiness severity. Timepoint: before intervention start, after intervention, 6,12,18,24, and 36 months after intervention as a follow-up phase. Method of measurement: by using self-report the subjective Emptiness Scale questionnaire.	—

Measure

Time frame

Anger severity. Timepoint: before intervention start, after intervention, 6,12,18,24, and 36 months after intervention as a follow-up phase. Method of measurement: by using self-report the State–Trait Anger Expression Inventory–2 questionnaire.;Dissociative symptoms severity. Timepoint: before intervention start, after intervention, 6,12,18,24, and 36 months after intervention as a follow-up phase. Method of measurement: by using self-report the dissociative Experiences Scale questionnaire.;Emotion dysregulation severity. Timepoint: before intervention start, after intervention, 6,12,18,24, and 36 months after intervention as a follow-up phase. Method of measurement: by using the Difficulties in Emotion Regulation Scale questionnaire.;Self-harm severity. Timepoint: before intervention start, after intervention, 6,12,18,24, and 36 months after intervention as a follow-up phase. Method of measurement: by using self-report the deliberate Self-Harm Inventory questionnaire.;Emptiness severity. Timepoint: before intervention start, after intervention, 6,12,18,24, and 36 months after intervention as a follow-up phase. Method of measurement: by using self-report the subjective Emptiness Scale questionnaire.

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Countries

Iran (Islamic Republic of)

Contacts

Public ContactBanafsheh Mohajerin

Shahid Beheshti University of Medical Sciences

banafshehmohajerin@gmail.com+98 912 578 6918

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026