The effect of consuming the prepared cakes with acorn flour in patients with metabolic syndrome

Comparison of the effect of consuming the prepared cakes with acorn flour and wheat flour following a hypocaloric diet on serum levels of adiponectin, inflammatory factors and oxidative stress parameters in obese and overweight patients with metabolic syndrome: a double-blind clinical trial

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20231104059958N1

Enrollment

Registered

2023-11-19

Start date

2022-06-22

Completion date

Unknown

Last updated

2024-01-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Condition 1: Metabolic syndrome. Condition 2: Obesity due to excess calories. Metabolic syndrome Obesity due to excess calories

Interventions

Intervention 1: Intervention group: the group that received the super-beneficial cake containing oak powder. The amount of calories in both oak and wheat cakes will be equal, so due to the higher calo

Eligibility

Sex/Gender

All

Age

20 Years to 60 Years

Inclusion criteria

Inclusion criteria: Patients with metabolic syndrome Waist circumference greater than 102 cm in men and 88 cm in women Triglycerides equal to or greater than 150 mg/dL HDL less than or equal to 40 in men and less than or equal to 50 in women Blood pressure more than 130 to 85 mm Hg and blood sugar equal to or more than 100 mg/dL Stable body weight (weight change less than 3 kg in the last 3 months) Not participating in weight loss programs in the last 6 months

Exclusion criteria

Exclusion criteria: Diabetic patients receiving blood sugar lowering drugs and insulin History of alcohol consumption Smoking Pregnant and lactating women People with mental illnesses, cancer, thyroid, cardiovascular, lung, kidney, liver, eating disorders Taking drugs that affect appetite, body weight, calcium and vitamin D metabolism, and lipid metabolism or have an anti-inflammatory effect. Taking antioxidants or multivitamins and any type of food supplement Having lactose intolerance

Design outcomes

Primary

Measure	Time frame
Interleukin-6. Timepoint: Before and after the intervention. Method of measurement: ELISA (Enzyme-Linked Immunosorbent Assay ) kit.;C reactive protein. Timepoint: Before and after the intervention. Method of measurement: ELISA (Enzyme-Linked Immunosorbent Assay ) kit.	—

Secondary

Measure	Time frame
Malondialdehyde. Timepoint: before and after the intervention. Method of measurement: Thiobarbituric acid method.;Total antioxidant capacity. Timepoint: before and after the intervention. Method of measurement: ElISA (Enzyme-linked immunosorbent assay) kit.;Adiponectin. Timepoint: before and after the intervention. Method of measurement: ElISA (Enzyme-linked immunosorbent assay) kit.	—

Countries

Iran (Islamic Republic of)

Contacts

Public Contacthamed sadeghi-dehsahraei

Faculty of Veterinary Medicine, Shiraz University

sadeghidehsahraiihamed@yahoo.com+98 71 3613 8618

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026