Macular amyloidosis. Organ-limited amyloidosis
Conditions
Interventions
Intervention 1: Intervention Group: Fractional Q-Switched Laser Group (Zone 1). Intervention 2: Intervention Group: co2 Laser Group (Zone 2). Intervention 3: Intervention Group: Combined Fractional Q-
Sponsors
Iran University of Medical Sciences
Eligibility
Sex/Gender
Female
Age
18 Years to 50 Years
Inclusion criteria
Inclusion criteria: Female patients aged 18 to 50 years Confirmed diagnosis of macular amyloidosis No prior laser treatment for the condition within the last three months Absence of significant underlying medical conditions Patient compliance with treatment protocols and ability to attend all therapy sessions Non-pregnant status and no plans for pregnancy within the next six months No active infections No hypersensitivity to retinoids or their derivatives No active rheumatologic diseases (e.g., lupus)
Exclusion criteria
Exclusion criteria: Development of hypersensitivity or any adverse reaction to the treatment interventions that would preclude continuation of therapy Pregnancy or plans for pregnancy within the next 6 months Active infection Active lupus or other active rheumatologic diseases Hypersensitivity to retinoids or their derivatives Immunodeficiency disorders Patient unwillingness to continue treatment
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Hyperpigmentation improvement percentage. Timepoint: Assessments were conducted at three timepoints: (1) baseline, (2) pre-second session (3 weeks later), and (3) 4 weeks after the second intervention. Method of measurement: photography- Doctor's evaluation- Patient's self-assessment. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactDr. Paria Jafary
Iran University of Medical Sciences
Outcome results
None listed