HACOR score in predicting non-invasive ventilation failure

Using HACOR score in predicting failure of non-invasive ventilation in patient with Type-I respiratory failure

Status

Active, not recruiting

Phases

Phase 2

Study type

Interventional

Source

IRCT

Registry ID

IRCT20231101059927N1

Enrollment

180

Registered

2023-11-07

Start date

2022-12-01

Completion date

Unknown

Last updated

2023-11-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Type-I respiratory failure. Acute respiratory failure

Interventions

Intervention group: HACOR SCORE GROUP.

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Patients with Pa02/FiO2 levels < 300 mmHg and PaCO2 levels less than 45 mmHg with PaO2 and PaCO2 (calculated by ABG (arterial blood gas) analysis) at room air or not maintaining ratio at low oxygenation therapy after administration of oxygen at FiO2 of 0.30

Exclusion criteria

Exclusion criteria: Patients with severe cardiorespiratory compromise Critical patients on vasopressor support Patients with poor lung compliance unable to breath in CPAP Intubated patients or those intubated less than 1 hour of CPAP Patients with a previous failed CPAP trial or on HFNO (high flow nasal oxygenation) in the last 72 hours Patients non-compliant on CPAP despite sedation Patients unwilling to be included in the study

Design outcomes

Primary

Measure	Time frame
Failure of NIV after 1-hour on CPAP therapy. Timepoint: 1 hour after CPAP therapy. Method of measurement: Standard HACOR score.;Sensitivity and specificity of HACOR in predicting NIV failure. Timepoint: 1 hour after being on CPAP therapy. Method of measurement: Assessment using standard SPSS software.;Postive and negative predictive value of the HACOR test in assessing NIV failure. Timepoint: 1 hour after being on CPAP therapy. Method of measurement: Standard statistical SPSS software.	—

Measure

Time frame

Failure of NIV after 1-hour on CPAP therapy. Timepoint: 1 hour after CPAP therapy. Method of measurement: Standard HACOR score.;Sensitivity and specificity of HACOR in predicting NIV failure. Timepoint: 1 hour after being on CPAP therapy. Method of measurement: Assessment using standard SPSS software.;Postive and negative predictive value of the HACOR test in assessing NIV failure. Timepoint: 1 hour after being on CPAP therapy. Method of measurement: Standard statistical SPSS software.

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Secondary

Measure	Time frame
Heart rate and mean arterial pressure. Timepoint: Before and after 1 hour of CPAP therapy. Method of measurement: Cardiac monitor.;Respiratory rate. Timepoint: Before and after 1 hour of CPAP therapy. Method of measurement: Standard respiratory monitor.;Glasgow coma scale. Timepoint: Before and after 1 hour of CPAP therapy. Method of measurement: Standard Glasgow coma scale.;Pa02/FiO2 ratio. Timepoint: Before and after 1 hour of CPAP therapy. Method of measurement: Using arterial blood gas samples and standard calculating formula.	—

Measure

Time frame

Heart rate and mean arterial pressure. Timepoint: Before and after 1 hour of CPAP therapy. Method of measurement: Cardiac monitor.;Respiratory rate. Timepoint: Before and after 1 hour of CPAP therapy. Method of measurement: Standard respiratory monitor.;Glasgow coma scale. Timepoint: Before and after 1 hour of CPAP therapy. Method of measurement: Standard Glasgow coma scale.;Pa02/FiO2 ratio. Timepoint: Before and after 1 hour of CPAP therapy. Method of measurement: Using arterial blood gas samples and standard calculating formula.

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Countries

Pakistan

Contacts

Public ContactAli Aftab

PNS Shifa Hospital Karachi

alijiwani512@hotmail.com+92 300 2509354

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026